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由于 Fahr 综合征引起的精神病病例,以及使用利培酮和奥卡西平治疗行为障碍的反应。

A case of psychosis due to Fahr's syndrome and response to behavioral disturbances with risperidone and oxcarbazepine.

机构信息

Department of Psychiatry, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital, Nagpur, Maharashtra, India.

出版信息

Indian J Psychiatry. 2014 Apr;56(2):188-90. doi: 10.4103/0019-5545.130506.

Abstract

Calcification of basal ganglia or Fahr's syndrome is a rare disease characterized by bilateral and symmetrical intracranial deposition of calcium mainly in cerebral basal ganglia. Motor and neuropsychiatric symptoms are prominent features. We report a case presented with a few motor symptoms, features of delirium and prominent psychiatric symptoms (disorganized behavior) predominantly evident after the improvement in delirium. Radiological findings were suggestive of bilateral basal ganglia calcification. Parathyroid hormone levels were low with no significant findings in other investigations and negative family history. Patient showed significant improvement in behavioral disturbances with risperidone, low dose of lorazepam, oxcarbazepine, and memantine.

摘要

基底节钙化或 Fahr 综合征是一种罕见的疾病,其特征是双侧和对称性颅内钙沉积,主要在大脑基底节。运动和神经精神症状是突出的特征。我们报告了一例以少量运动症状、意识障碍特征和突出的精神症状(行为紊乱)为主要表现的病例,这些症状主要在意识障碍改善后出现。影像学发现提示双侧基底节钙化。甲状旁腺激素水平低,其他检查无明显异常,家族史阴性。患者在使用利培酮、低剂量劳拉西泮、奥卡西平、美金刚治疗后,行为紊乱显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/929c/4040070/6863fbbc6da0/IJPsy-56-188-g001.jpg

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