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[委内瑞拉苏利亚州帕埃斯区人群中针对委内瑞拉马脑炎病毒的抗体]

[Antibodies against the Venezuelan equine encephalitis virus in the population of the Páez District of the Zulia Venezuela State].

作者信息

Ryder S

出版信息

Invest Clin. 1989;30(1):3-11.

PMID:2489273
Abstract

With the purpose of knowing the presence of antibodies against Venezuelan Equine Encephalities virus (EEV), after the continuous outbreaks produced by this virus we studied 192 sera (112 children and 80 adults), from the towns of Carretal, Cojoro and Paraguaipoa (Páez District), between the months of March and October 1986. The samples were analyzed using the hemagglutination inhibition test by the Clarke and Casals technique, using VEE virus antigen Guajira strain. We found that from 192 samples, 161 were negative 84%. This negativity was observed mainly on the infant population where it reached 97%. Negativity in adults was 65%. These results demonstrate that there has been no viral activity since the last outbreak in 1973, due probably to the epidemiological controls done on that zone and that the percentage of positivity of those older than 15 years has maintained the same level since the last survey on 1973.

摘要

为了解委内瑞拉马脑炎病毒(EEV)抗体的存在情况,在该病毒持续爆发后,我们于1986年3月至10月期间,对来自卡雷塔尔、科霍罗和帕拉瓜伊波阿(派斯区)城镇的192份血清(112名儿童和80名成人)进行了研究。采用克拉克和卡萨尔斯技术的血凝抑制试验,使用瓜希拉株VEE病毒抗原对样本进行分析。我们发现,192份样本中有161份呈阴性,占84%。这种阴性主要出现在婴儿群体中,达到了97%。成人的阴性率为65%。这些结果表明,自1973年最后一次疫情爆发以来,该地区可能由于采取了流行病学控制措施,未出现病毒活动,且自1973年上次调查以来,15岁以上人群的阳性率一直保持在同一水平。

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