Ryder S, Núñez-Camargo J, Rangel P, Añez F
Instituto de Investigaciones Clínicas, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela.
Invest Clin. 1993;34(3):135-41.
With the purpose of determining antibodies prevalence against Venezuelan Equine Encephalitis Virus in the population of Puertos de Altagracia and Sabaneta de Palmas of Miranda county, Zulia State, Venezuela, 199 subjects were studied: 57 from Puertos de Altagracia and 142 from Sabaneta de Palmas. They were classified in older (42.78%) and younger (57.2%) than 15 years. The blood specimens were processed for Hemagglutination Inhibition Test using EEV antigen Goajira strain at pH 6.5. We found that all 57 specimens from Puertos de Altagracia were negative, whereas of 142 specimens from Sabaneta de Palmas 17 were positive (11.97%). Of these, one was from a subject less than 15 years-old (5.85%) and 16 from individuals more than 15 years-old (94.15%). Positive titers were higher than 1:160 in 80% of cases. Being Sabaneta de Palmas one of the most affected areas in the 1962 epidemic in the Miranda county and keeping the affected ones high positivity with elevated titers, we conclude that this population could represent an enzootic zone similar to Paez county where a similar situation, of high positivity and elevated titers, many years after the last epidemic occurred in that area, has been described.
为了确定委内瑞拉苏利亚州米兰达州阿尔塔格拉西亚港和帕尔马斯的萨瓦内塔人群中抗委内瑞拉马脑炎病毒抗体的流行情况，对199名受试者进行了研究：其中57名来自阿尔塔格拉西亚港，142名来自帕尔马斯的萨瓦内塔。他们被分为15岁以上（42.78%）和15岁以下（57.2%）两组。血液样本使用EEV抗原戈亚吉拉毒株在pH 6.5条件下进行血凝抑制试验。我们发现，来自阿尔塔格拉西亚港的所有57个样本均为阴性，而来自帕尔马斯的萨瓦内塔的142个样本中有17个呈阳性（11.97%）。其中，1个样本来自一名15岁以下的受试者（5.85%），16个样本来自15岁以上的个体（94.15%）。80%的病例阳性滴度高于1:160。由于帕尔马斯的萨瓦内塔是米兰达州1962年疫情中受影响最严重的地区之一，且感染者保持着高阳性率和高滴度，我们得出结论，该人群可能代表一个与派斯县类似的地方病流行区，在该地区最后一次疫情发生多年后，那里也出现了类似的高阳性率和高滴度情况。
