Larson Janet L, Vos Carol M, Fernandez Dena
Annu Rev Nurs Res. 2013;31:297-326. doi: 10.1891/0739-6686.31.297.
People with chronic obstructive pulmonary disease (COPD) are very sedentary and this contributes to their health problems. The aim of this systematic review was to examine the effects of interventions designed to increase physical activity (PA) in people with COPD. Studies were included when PA was the primary outcome and measured objectively. Six databases were searched and 15 studies with a total of 761 subjects were identified that met inclusion criteria. Nine of the studies were quasi-experimental (QE) and six were randomized controlled trials (RCT). Interventions included pulmonary rehabilitation (n = 7), exercise only (n = 2), behavioral only (n = 2) and a combination of both behavioral and pulmonary rehabilitation/exercise interventions (n = 4). Methodological quality was evaluated using the Downs and Black checklist. The quality of the pulmonary rehabilitation studies was the lowest with a fair rating and the quality of exercise only studies was the highest with a good rating. Eight of the 15 studies demonstrated statistically significant increases in PA: two pulmonary rehabilitation (QE = 2), two exercise only (RCT = 2), two behavioral only (RCT = 1, QE = 1), and two combined behavioral and pulmonary rehabilitation/exercise (RCT = 2). The magnitude of increase was modest in all but one study; and in many studies the increase in PA was not clinically meaningful. Longer interventions demonstrated a higher success rate and only three studies examined longer term effects of the interventions. Existing interventions are promising, but the small number of randomized controlled trials makes it difficult to draw conclusion. Further research is needed to identify a range of interventions that are effective and could be used to promote PA in people with COPD.
慢性阻塞性肺疾病(COPD)患者久坐不动,这加剧了他们的健康问题。本系统评价的目的是研究旨在增加COPD患者身体活动(PA)的干预措施的效果。当PA为主要结局且采用客观测量时纳入研究。检索了六个数据库,共识别出15项研究、761名受试者符合纳入标准。其中9项研究为准实验性研究(QE),6项为随机对照试验(RCT)。干预措施包括肺康复(n = 7)、单纯运动(n = 2)、单纯行为干预(n = 2)以及行为与肺康复/运动干预相结合(n = 4)。使用唐斯和布莱克检查表评估方法学质量。肺康复研究的质量最低,评定为一般,单纯运动研究的质量最高,评定为良好。15项研究中有8项显示PA有统计学意义的增加:两项肺康复研究(QE = 2),两项单纯运动研究(RCT = 2),两项单纯行为干预研究(RCT = 1,QE = 1),以及两项行为与肺康复/运动相结合的研究(RCT = 2)。除一项研究外,所有研究中PA增加的幅度都较小;在许多研究中,PA的增加在临床上并无意义。较长时间的干预显示出更高的成功率,只有三项研究考察了干预措施的长期效果。现有干预措施很有前景,但随机对照试验数量较少,难以得出结论。需要进一步研究以确定一系列有效的干预措施,用于促进COPD患者的身体活动。