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IL-6 strikes a balance in metabolic inflammation.
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Immunometabolism: IL-6, the resistance fighter.
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Countering inflammatory signals in obesity.
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The good, the bad, and the ugly of interleukin-6 signaling.
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6
Versatile functions for IL-6 in metabolism and cancer.
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Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia.
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IL-29 promoted obesity-induced inflammation and insulin resistance.
Cell Mol Immunol. 2020 Apr;17(4):369-379. doi: 10.1038/s41423-019-0262-9. Epub 2019 Jul 30.

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Macronutrient-differential dietary pattern impacts on body weight, hepatic inflammation, and metabolism.
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Integrative bioinformatics analysis to screen key genes and signalling pathways related to ferroptosis in obesity.
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Effects of Leptin and Body Weight on Inflammation and Knee Osteoarthritis Phenotypes in Female Rats.
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A Web-Based Method for the Identification of IL6-Based Immunotoxicity in Vaccine Candidates.
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Transcriptome profiling reveals stress-responsive gene networks in cattle muscles.
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1
Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice.
Am J Physiol Regul Integr Comp Physiol. 2014 Jun 1;306(11):R861-7. doi: 10.1152/ajpregu.00533.2013. Epub 2014 Apr 2.
3
Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications.
Am J Physiol Endocrinol Metab. 2013 Mar 1;304(5):E453-65. doi: 10.1152/ajpendo.00553.2012. Epub 2012 Dec 31.
4
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis.
Nature. 2011 Nov 20;480(7375):104-8. doi: 10.1038/nature10653.
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Macrophage-mediated inflammation in metabolic disease.
Nat Rev Immunol. 2011 Oct 10;11(11):738-49. doi: 10.1038/nri3071.
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The pro- and anti-inflammatory properties of the cytokine interleukin-6.
Biochim Biophys Acta. 2011 May;1813(5):878-88. doi: 10.1016/j.bbamcr.2011.01.034. Epub 2011 Feb 4.
7
Inflammatory mechanisms in obesity.
Annu Rev Immunol. 2011;29:415-45. doi: 10.1146/annurev-immunol-031210-101322.
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Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue.
J Clin Invest. 2010 Oct;120(10):3466-79. doi: 10.1172/JCI42845. Epub 2010 Sep 27.
9
Point: Interleukin-6 does have a beneficial role in insulin sensitivity and glucose homeostasis.
J Appl Physiol (1985). 2007 Feb;102(2):814-6. doi: 10.1152/japplphysiol.01208.2006. Epub 2006 Oct 26.
10
Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient mice.
Am J Physiol Regul Integr Comp Physiol. 2006 Sep;291(3):R551-7. doi: 10.1152/ajpregu.00514.2005.

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