Tanaka Kenichi, Aoki-Kinoshita Kiyoko F, Kotera Masaaki, Sawaki Hiromichi, Tsuchiya Shinichiro, Fujita Noriaki, Shikanai Toshihide, Kato Masaki, Kawano Shin, Yamada Issaku, Narimatsu Hisashi
Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST) , Tsukuba, Ibaraki 305-8568, Japan.
J Chem Inf Model. 2014 Jun 23;54(6):1558-66. doi: 10.1021/ci400571e. Epub 2014 Jun 4.
In recent years, the Semantic Web has become the focus of life science database development as a means to link life science data in an effective and efficient manner. In order for carbohydrate data to be applied to this new technology, there are two requirements for carbohydrate data representations: (1) a linear notation which can be used as a URI (Uniform Resource Identifier) if needed and (2) a unique notation such that any published glycan structure can be represented distinctively. This latter requirement includes the possible representation of nonstandard monosaccharide units as a part of the glycan structure, as well as compositions, repeating units, and ambiguous structures where linkages/linkage positions are unidentified. Therefore, we have developed the Web3 Unique Representation of Carbohydrate Structures (WURCS) as a new linear notation for representing carbohydrates for the Semantic Web.
近年来，语义网已成为生命科学数据库开发的焦点，它是一种有效且高效地链接生命科学数据的手段。为了使碳水化合物数据能够应用于这项新技术，碳水化合物数据表示有两个要求：（1）一种线性表示法，如有需要可作为统一资源标识符（URI）使用；（2）一种唯一表示法，以便任何已发表的聚糖结构都能被独特地表示。后一个要求包括将非标准单糖单元作为聚糖结构的一部分进行可能的表示，以及组成、重复单元和连接/连接位置不明的模糊结构。因此，我们开发了碳水化合物结构的网络3唯一表示法（WURCS），作为一种用于语义网表示碳水化合物的新线性表示法。
