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具有心血管专业资质的药剂师对心肌梗死和心力衰竭的过程指标及结局的影响。

The effect of cardiovascular credentialed pharmacists on process measures and outcomes in myocardial infarction and heart failure.

作者信息

Dorsch Michael P, Lose Jennifer M, DiDomenico Robert J

机构信息

Department of Pharmacy Services, College of Pharmacy, University of Michigan Hospitals and Health Centers, Ann Arbor, Michigan.

出版信息

Pharmacotherapy. 2014 Aug;34(8):803-8. doi: 10.1002/phar.1444. Epub 2014 Jun 5.

Abstract

OBJECTIVE

The purpose of this study was to determine if institutions with inpatient cardiovascular credentialed pharmacists exhibit improved quality measures for acute myocardial infarction (AMI) and heart failure (HF) care compared with institutions without inpatient cardiovascular credentialed pharmacists.

METHODS

We conducted a multicenter, retrospective, cross-sectional, matched case-control study. Hospitals with at least one Added Qualification in Cardiology (AQCV) inpatient pharmacist were included in the case group. Each case group hospital was matched to hospitals without an AQCV pharmacist by region, number of cardiovascular discharges, and teaching hospital designation in a 1:3 ratio (case:control). The 34 AQCV hospitals were matched to 102 non-AQCV hospitals. The proportions of discharges meeting HF and AMI process of care measures and 30-day outcomes (readmission and mortality) for each hospital were determined from public data and compared between the case and control groups.

RESULTS

Hospitals with AQCV pharmacists performed better on process of care measures than hospitals without AQCV pharmacists (odds ratio 1.41, 95% confidence interval 1.25-1.58, p<0.0001, p<0.001 for heterogeneity), which was mainly driven by the aspirin on discharge for AMI and angiotensin-converting enzyme inhibitor or angiotensin receptor blocker on discharge for HF measures. No differences were observed between the groups for either readmission or mortality at 30 days.

CONCLUSIONS

Hospitals that used inpatient AQCV pharmacists performed better on process of care measures than hospitals that do not use inpatient AQCV pharmacists. However, improvements in process of care performance measures observed in AQCV hospitals did not translate into improved 30-day clinical outcomes.

摘要

目的

本研究旨在确定与没有住院心血管专科认证药师的机构相比,拥有住院心血管专科认证药师的机构在急性心肌梗死(AMI)和心力衰竭(HF)护理方面的质量指标是否有所改善。

方法

我们开展了一项多中心、回顾性、横断面、匹配病例对照研究。病例组纳入了至少有一名具备心脏病学附加资格(AQCV)的住院药师的医院。病例组的每家医院按地区、心血管疾病出院人数和教学医院指定情况与没有AQCV药师的医院以1:3的比例(病例:对照)进行匹配。34家AQCV医院与102家非AQCV医院进行了匹配。从公开数据中确定每家医院符合HF和AMI护理流程指标及30天结局(再入院和死亡率)的出院比例,并在病例组和对照组之间进行比较。

结果

拥有AQCV药师的医院在护理流程指标方面比没有AQCV药师的医院表现更好(优势比1.41,95%置信区间1.25 - 1.58,p<0.0001,异质性p<0.001),这主要由AMI出院时使用阿司匹林以及HF指标出院时使用血管紧张素转换酶抑制剂或血管紧张素受体阻滞剂驱动。两组在30天的再入院率或死亡率方面均未观察到差异。

结论

使用住院AQCV药师的医院在护理流程指标方面比未使用住院AQCV药师的医院表现更好。然而,在AQCV医院观察到的护理流程绩效指标改善并未转化为30天临床结局的改善。

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