用于合成α-氟代酮的烯烃无金属高效氧氟化反应

Metal-free, efficient oxyfluorination of olefins for the synthesis of α-fluoroketones.

作者信息

Yang Qiang, Mao Liu-Liang, Yang Bin, Yang Shang-Dong

机构信息

State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, P. R. China.

出版信息

Org Lett. 2014 Jul 3;16(13):3460-3. doi: 10.1021/ol501357w. Epub 2014 Jun 5.

DOI:10.1021/ol501357w

PMID:24901370

Abstract

A novel oxyfluorination of olefin reactions has been developed. The reactions involve a metal-free and green catalytic system for the synthesis of α-fluoroketones which is an important building block for organic synthesis. Moreover, this reaction system exhibits great functional group tolerance.

摘要

已开发出一种新型的烯烃氧氟化反应。这些反应涉及一种用于合成α-氟代酮的无金属绿色催化体系，α-氟代酮是有机合成的重要结构单元。此外，该反应体系具有良好的官能团耐受性。