Harrison Beth T, Berg Robert E, Mittal Khush
Departments of Pathology (B.T.H., K.M.) Obstetrics and Gynecology (R.E.B.), New York University Langone Medical Center, New York, New York.
Int J Gynecol Pathol. 2014 Jul;33(4):418-22. doi: 10.1097/PGP.0b013e31829d76ee.
Massive ovarian edema is a rare disorder in which there is marked accumulation of interstitial fluid in the stroma of the ovary. Grossly, the involved ovary is an enlarged solid mass with a smooth tan-white surface, easily confused with a neoplasm. Microscopically, it features diffuse interstitial edema sparing follicles and outer cortex, dilated lymphatic vessels, thick-walled veins, fibromatosis, and luteinized stromal cells. It is believed that massive ovarian edema arises from interference in lymphatic drainage and venous return of the ovary secondary to partial torsion among other etiologies. Herein we provide the first description of unilateral ovarian edema in association with a large leiomyoma in the ipsilateral broad ligament. It is important to recognize the various presentations of this benign entity and to consider it in the differential diagnosis of an adnexal mass in a reproductive age woman.
巨大卵巢水肿是一种罕见的疾病，其特征为卵巢间质中出现大量间质液积聚。大体上，受累卵巢是一个增大的实性肿块，表面光滑，呈棕白色，易与肿瘤混淆。显微镜下，其特征为弥漫性间质水肿，不累及卵泡和外层皮质，淋巴管扩张，静脉壁增厚，纤维瘤病，以及黄素化的间质细胞。据信，巨大卵巢水肿是由卵巢淋巴引流和静脉回流受干扰引起的，继发于部分扭转等病因。在此，我们首次描述了单侧卵巢水肿与同侧阔韧带内大的平滑肌瘤相关的情况。认识到这种良性病变的各种表现，并在育龄妇女附件肿块的鉴别诊断中考虑到它，是很重要的。
