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[神经损伤与创伤后治疗]

[Nerve injuries and posttraumatic therapy].

作者信息

Radtke C, Vogt P M

机构信息

Klinik und Poliklinik für Plastische, Hand- und Wiederherstellungschirurgie, Medizinische Hochschule Hannover, Carl-Neuberg-Straße 1, 30625, Hannover, Deutschland,

出版信息

Unfallchirurg. 2014 Jun;117(6):539-55; quiz 556. doi: 10.1007/s00113-014-2574-7.

DOI:10.1007/s00113-014-2574-7
PMID:24903504
Abstract

Peripheral nerve injuries are a common clinical problem and can represent a major challenge, especially after trauma. In order to achieve optimal therapy, an early and adequate diagnosis with subsequent therapy is critical for functional preservation and restoration. Especially after complete severance of a peripheral nerve, the surgical techniques for nerve coaptation are an important prerequisite for peripheral nerve regeneration. The importance and necessity of adequate nerve coaptation and nerve transplantation are presented in detail. In addition, the types of primary and secondary nerve reconstruction procedures are described as well as the optimal time point of nerve repair. This article provides a comprehensive overview of the possibilities for diagnosis and intervention after nerve injury, additionally including an algorithm for surgical intervention. Furthermore, possible pitfalls and factors for improving the functional outcome are presented to optimize results with trauma-related nerve injury.

摘要

周围神经损伤是常见的临床问题,可能构成重大挑战,尤其是在创伤后。为实现最佳治疗效果,早期且充分的诊断以及后续治疗对于功能的保留和恢复至关重要。特别是在周围神经完全离断后,神经吻合的外科技术是周围神经再生的重要前提。文中详细阐述了充分神经吻合和神经移植的重要性及必要性。此外,还描述了一期和二期神经重建手术的类型以及神经修复的最佳时间点。本文全面概述了神经损伤后诊断和干预的可能性,还包括手术干预的算法。此外,还介绍了可能存在的陷阱以及改善功能结果的因素,以优化创伤相关神经损伤的治疗效果。

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[Use of acellular allogeneic nerve transplants for nerve defects of the hand : Experience from a German hand surgery center].

本文引用的文献

1
A systematic review on the use of fibrin glue for peripheral nerve repair.纤维蛋白胶在周围神经修复中的应用的系统评价。
Plast Reconstr Surg. 2011 Jun;127(6):2381-2390. doi: 10.1097/PRS.0b013e3182131cf5.
2
Home-based functional electrical stimulation rescues permanently denervated muscles in paraplegic patients with complete lower motor neuron lesion.家庭功能性电刺激可挽救完全性下运动神经元损伤截瘫患者的永久性失神经肌肉。
Neurorehabil Neural Repair. 2010 Oct;24(8):709-21. doi: 10.1177/1545968310366129. Epub 2010 May 11.
3
Chapter 8: Current techniques and concepts in peripheral nerve repair.
[脱细胞异体神经移植治疗手部神经缺损:来自德国一家手外科中心的经验]
Unfallchirurgie (Heidelb). 2022 Nov;125(11):892-896. doi: 10.1007/s00113-022-01143-6. Epub 2022 Feb 15.
4
[Neuromuscular complications of fractures of the extremities, part 2 : Nerve injuries and iatrogenic damage].[四肢骨折的神经肌肉并发症,第2部分:神经损伤和医源性损伤]
Unfallchirurg. 2020 Mar;123(3):225-237. doi: 10.1007/s00113-020-00768-9.
5
[Humeral shaft fractures].[肱骨干骨折]
Unfallchirurg. 2018 Sep;121(9):747-758. doi: 10.1007/s00113-018-0533-4.
6
[Update on gunshot wounds to extremities].[四肢枪伤的最新情况]
Unfallchirurg. 2018 Jan;121(1):59-72. doi: 10.1007/s00113-017-0449-4.
7
[Soft tissue sarcoma: how can posttreatment alterations be distinguished from recurrences?].[软组织肉瘤:如何区分治疗后改变与复发?]
Radiologe. 2017 Nov;57(11):923-937. doi: 10.1007/s00117-017-0310-3.
8
[Diagnostic ability of power measurement of different grip forms for distal median nerve lesion].[不同握力形式下力量测量对正中神经远端损伤的诊断能力]
Unfallchirurg. 2018 Mar;121(3):230-238. doi: 10.1007/s00113-017-0323-4.
9
[Regeneration of a radial nerve after compression under an osteosynthesis plate].[接骨板下压迫后桡神经的再生]
Unfallchirurg. 2017 Mar;120(3):257-261. doi: 10.1007/s00113-016-0264-3.
第8章:周围神经修复的当前技术与概念
Int Rev Neurobiol. 2009;87:141-72. doi: 10.1016/S0074-7742(09)87008-6.
4
Neuronal death after peripheral nerve injury and experimental strategies for neuroprotection.周围神经损伤后的神经元死亡及神经保护的实验策略。
Neurol Res. 2008 Dec;30(10):999-1011. doi: 10.1179/174313208X362479.
5
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J Clin Neuromuscul Dis. 2006 Mar;7(3):97-103. doi: 10.1097/01.cnd.0000203641.38887.63.
6
Management of radial nerve injury associated with humeral shaft fractures: an evidence-based approach.肱骨干骨折相关桡神经损伤的管理:循证方法
J Reconstr Microsurg. 2008 Nov;24(8):569-73. doi: 10.1055/s-0028-1090623. Epub 2008 Oct 16.
7
Laser phototherapy (780 nm), a new modality in treatment of long-term incomplete peripheral nerve injury: a randomized double-blind placebo-controlled study.激光光疗(780纳米),一种治疗长期不完全性周围神经损伤的新方法:一项随机双盲安慰剂对照研究。
Photomed Laser Surg. 2007 Oct;25(5):436-42. doi: 10.1089/pho.2007.2093.
8
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Zentralbl Neurochir. 2007 Aug;68(3):101-10. doi: 10.1055/s-2007-984453. Epub 2007 Jul 30.
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