Garcia-Villarreal Ovidio A, Fernández-Ceseña Ernesto, Solano-Ricardi Mercedes, Aguilar-García Alma L, Vega-Hernández Raquel, Del Angel-Soto Gustavo
Department of Cardiac Surgery, Hospital of Cardiology, UMAE 34, IMSS, Monterrey, Nuevo Leon, Mexico
Department of Cardiology, Hospital of Cardiology, UMAE 34, IMSS, Monterrey, Nuevo Leon, Mexico.
Asian Cardiovasc Thorac Ann. 2016 Jan;24(1):57-9. doi: 10.1177/0218492314539333. Epub 2014 Jun 5.
We report the case of 23-year-old man with mitral valve regurgitation and Glanzmann thrombasthenia, who underwent mechanical mitral valve replacement. Warfarin therapy was devastating, causing bilateral hemothorax, pericardial effusion, gastrointestinal bleeding, and hematuria. Redo mitral valve replacement with a biological prosthesis was required to resolve this critical situation. To our knowledge, this is the first report of mitral valve replacement in Glanzmann thrombasthenia, highlighting the danger of oral anticoagulation in this pathology.
我们报告了一名23岁患有二尖瓣反流和Glanzmann血小板无力症的男性病例，该患者接受了二尖瓣机械瓣膜置换术。华法林治疗带来了灾难性后果，导致双侧血胸、心包积液、胃肠道出血和血尿。为解决这一危急情况，需要再次进行二尖瓣置换术，使用生物假体。据我们所知，这是关于Glanzmann血小板无力症患者二尖瓣置换术的首例报告，突出了这种疾病口服抗凝治疗的危险性。
