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[肺炎球菌肺炎患者痰液中的抗体包被细菌]

[Antibody-coated bacteria in the sputum from patients with pneumococcal pneumonia].

作者信息

Sala-Mateus C, Puig de la Bellacasa J, Torres A, Jiménez de Anta M T, Hojman L, Agustí A

出版信息

Enferm Infecc Microbiol Clin. 1989 Jan;7(1):36-9.

PMID:2490640
Abstract

In the present study an immunofluorescence technique detecting antibody-coated bacteria was evaluated. It was applied to the sputum of seven patients with bacteremic pneumococcal pneumonia to assess its diagnostic usefulness. We conclude that it is a valid, quick and easy technique which permits to differentiate between bacteria contaminating the sputum from those involved in the infection. This gives, therefore, a new value to the study of sputum. In our series the duration of the disease had no influence on the results, and the three antigammaglobulins used (anti-IgG, anti-IgA and anti-IgM) yielded the same results in each sample. Thus, we feel that the local pulmonary immune response was secondary in type.

摘要

在本研究中,对一种检测抗体包被细菌的免疫荧光技术进行了评估。该技术应用于7例菌血症性肺炎球菌肺炎患者的痰液,以评估其诊断价值。我们得出结论,这是一种有效、快速且简便的技术,能够区分污染痰液的细菌与感染相关的细菌。因此,这为痰液研究赋予了新的价值。在我们的系列研究中,疾病持续时间对结果没有影响,并且所使用的三种抗γ球蛋白(抗IgG、抗IgA和抗IgM)在每个样本中都产生了相同的结果。因此,我们认为局部肺部免疫反应在类型上是次要的。

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