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[1987年马德里,人类免疫缺陷病毒感染的异性传播]

[Heterosexual transmission of HIV infection, Madrid 1987].

作者信息

de la Loma A, García S, del Romero J, Neila M A, Ramos P

出版信息

Enferm Infecc Microbiol Clin. 1989 Mar;7(3):135-9.

PMID:2490680
Abstract

Seven males of 132 (5%) and 9 females of 85 (10%) out of 217 heterosexual individuals without addiction to drugs or previous blood transfusion who attended a STD clinic in Madrid because they had high risk sexual partners were found to have antiHIV antibodies by ELISA and immunofluorescence (CNMVIS). However, when variables such as sex, promiscuity and sexual habits were correlated with HIV infection, significant differences were not found between seropositive and seronegative individuals (kappa 2, p greater than 0.05). Among the factors statistically linked with the infection (kappa 2, p less than 0.05) there were the previous STD and the sustained sexual intercourse with proven HIV seropositive individuals: there 8 infected individuals out of 40 with such type of partners (relative risk 4.4). On the other hand, the partners of individuals with unknown serological findings had the following results: 4 seropositive individuals out of 71 partners of parenteral drug abusers, 3 of 82 users of prostitutes, and 1 infected individual out of the 24 remaining ones (partners of bisexual individuals or combinations) (relative risk of each of them less than 1). These results show the importance of heterosexual, not mediated by blood, HIV transmission in couples of high risk persons, and they suggest that the infection is highly likely if sexual intercourse is maintained with infected individuals irrespective of their sex.

摘要

在马德里一家性病诊所就诊的217名无药物成瘾史或既往无输血史的异性恋个体中,有7名男性(132人中的5%)和9名女性(85人中的10%)因有高危性伴侣而被酶联免疫吸附测定(ELISA)和免疫荧光法(CNMVIS)检测出抗HIV抗体。然而,当将性别、滥交和性行为习惯等变量与HIV感染进行相关性分析时,血清阳性和血清阴性个体之间未发现显著差异(卡方值为2,p大于0.05)。在与感染有统计学关联的因素中(卡方值为2,p小于0.05),有既往性传播疾病史以及与经证实的HIV血清阳性个体持续发生性行为:在有此类性伴侣的40人中,有8人感染(相对风险为4.4)。另一方面,血清学结果未知个体的性伴侣有以下情况:在71名注射吸毒者的性伴侣中有4名血清阳性个体,在82名嫖客中有3名,在其余24名(双性恋个体或混合性别的性伴侣)中有1名感染个体(他们各自的相对风险均小于1)。这些结果表明,在高危人群的异性恋伴侣中,非血液介导的HIV传播很重要,并且提示如果与感染个体保持性行为,无论其性别如何,感染的可能性都很高。

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