皮肤移植术后静脉溃疡患者疼痛情况的评估
Evaluation of pain in patients with venous ulcers after skin grafting.
作者信息
Salomé Geraldo Magela, de Almeida Sergio Aguinaldo, Ferreira Lydia Masako
机构信息
Graduate Program in Plastic Surgery, Federal University of São Paulo (UNIFESP), Av. Francisco de Paula Quintanilha Ribeiro 280, Apt. 134, CEP 04330-020 São Paulo, SP, Brazil.
Private Practice in São Paulo, Brazil.
出版信息
J Tissue Viability. 2014 Aug;23(3):115-20. doi: 10.1016/j.jtv.2014.04.004. Epub 2014 May 16.
AIM
Pain was assessed in patients with venous leg ulcers treated with either split-thickness skin grafts or conventional treatment to evaluate to what extent skin grafting reduces pain in this population.
METHODS
A controlled prospective clinical trial was conducted from July 2008 to June 2011 in two hospitals in São Paulo, Brazil. Two hundred patients with venous leg ulcers were divided into two treatment groups of 100 patients each: control group (conservative treatment) and surgery group (skin grafting). Patients were assessed at baseline (day 0) and after 30, 90, and 180 days.
RESULTS
The surgery group reported significantly lower pain intensity (VAS pain scores) at postoperative days 30, 90 and 180 days compared with controls (P = 0.0001). The McGill Pain Questionnaire was used to assess the sensory, affective, evaluative, and miscellaneous dimensions of pain in both groups; there were significant differences between groups at the time points 30, 90 and 180 days (P = 0.0001).
CONCLUSION
The patients with venous leg ulcers treated with split-thickness skin grafts reported significantly lower pain intensity compared with those who received conservative treatment.
目的
对接受分层皮片移植或传统治疗的下肢静脉性溃疡患者进行疼痛评估，以评估皮肤移植在多大程度上减轻该人群的疼痛。
方法
2008年7月至2011年6月在巴西圣保罗的两家医院进行了一项对照前瞻性临床试验。200例下肢静脉性溃疡患者被分为两个治疗组，每组100例：对照组（保守治疗）和手术组（皮肤移植）。在基线（第0天）以及术后30、90和180天对患者进行评估。
结果
与对照组相比，手术组在术后第30、90和180天报告的疼痛强度（视觉模拟评分疼痛分数）显著更低（P = 0.0001）。使用麦吉尔疼痛问卷评估两组疼痛的感觉、情感、评价和其他维度；在第30、90和180天时间点两组之间存在显著差异（P = 0.0001）。
结论
与接受保守治疗的患者相比，接受分层皮片移植治疗的下肢静脉性溃疡患者报告的疼痛强度显著更低。
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