Althaf Mohammed Mahdi, Abdelsalam Mohamed Said, Rashwan Mohamed, Nadri Quaid
Department of Medicine, Section of Nephrology, King Faisal Specialist Hospital and Research Center, Riyadh, Ar-Riyadh, Saudi Arabia.
Department of Medicine, Section of Nephrology, King Faisal Specialist Hospital and Research Center, Riyadh, Ar-Riyadh, Saudi Arabia Internal Medicine Department, Alexandria University, Faculty of Medicine, Alexandria, Egypt.
BMJ Case Rep. 2014 Jun 6;2014:bcr2014203643. doi: 10.1136/bcr-2014-203643.
We present a case where a renal transplant recipient contracted chronic hepatitis C virus (HCV) infection post-transplantation. The disease progressed and deteriorated leading to fibrosing cholestatic hepatitis that mandated treatment. Treatment with pegylated interferon α-2a and ribavirin was successful in salvaging the liver and eradicating the virus but as a consequence lead to treatment-resistant acute rejection and loss of the renal allograft.
我们报告了一例肾移植受者在移植后感染慢性丙型肝炎病毒（HCV）的病例。疾病进展并恶化，导致纤维性胆汁淤积性肝炎，需要进行治疗。聚乙二醇化干扰素α-2a和利巴韦林治疗成功挽救了肝脏并清除了病毒，但结果导致了治疗抵抗性急性排斥反应和肾移植受者丧失。
