Department of Neurosurgery, Case Western University School of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA; Department of Neurosurgery, Mansoura University School of Medicine, University Hospitals, Mansoura, Egypt.
Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA; Center for Spine Health, Cleveland Clinic, Cleveland, Ohio, USA.
World Neurosurg. 2014 Nov;82(5):855-65. doi: 10.1016/j.wneu.2014.05.034. Epub 2014 Jun 4.
Pedicle fractures in the cervical spine are common. They may occur in isolation or in combination with other concomitant fractures. Multiple classification systems have been introduced to provide a clinical framework when approaching these types of fractures; however, these systems do not provide guidelines for optimal treatment. Data regarding decision making are limited. Conservative treatment with orthoses may result in subluxation and instability requiring further treatment. Surgery may not be required in all instances because many of these injuries may heal without surgical intervention.
All cases of cervical fractures treated at a single institution over a 5-year period were retrospectively reviewed. Cases with pedicle fractures were further evaluated, and 40 cases managed either with or without surgery were identified. Data on presenting history, neurologic examination, imaging findings, comorbidity, method of treatment, complication rate, and length of hospital stay were collected. Fractures were classified based on computed tomography scans. Data on associated injuries were also collected. Fusion rate and fracture displacement were assessed by plain radiographs and computed tomography scans at follow-up. Follow-up time points included 2, 6, and 12 weeks and 6 months after injury. Primary outcome was fracture healing regardless of modality in the absence of progressive deformity (i.e., listhesis, kyphosis) and need for further surgery.
Conservative therapy was administered to 26 patients, and 14 patients underwent surgery. There were no statistically significant differences between the 2 groups in terms of total levels injured (P = 0.9) or injury severity score (P = 0.5). Patients who presented with intact neurologic status were more likely to be treated conservatively (88% vs. 29%; P = 0.0004), whereas patients presenting with spinal cord injuries were more likely to undergo surgical fixation (35% vs. 0%; P = 0.0004). Length of hospital stay trended toward being significantly greater in patients who underwent surgery (10.6 days vs. 5.5 days; P = 0.07). According to our classification system, the most common fracture type was single line horizontal fracture occurring in 68% (27 of 40 cases). Vertical split pedicle fracture occurred in 28% (11 of 40 cases), and double line horizontal fracture occurred in 5% (2 of 40 cases). Posttreatment progressive listhesis was significantly higher in patients who were treated conservatively (31% vs. 0%; P = 0.03), especially when associated with comminuted lateral mass or subluxation or both.
This study describes and classifies unique cervical pedicle fractures and associated injuries. Our findings suggest that surgical treatment results in definitive stability for these injuries compared with conservative therapy, particularly for pedicle fractures associated with comminuted lateral mass or initially displaced fractures. However, nondisplaced vertical split pedicle fractures and isolated single line horizontal fractures may be treated nonsurgically without occurrence of further instability. A larger prospective study is required to confirm these findings.
颈椎椎弓根骨折很常见。它们可能单独发生,也可能与其他伴随骨折一起发生。已经引入了多种分类系统,为这些类型的骨折提供临床框架;然而,这些系统并没有为最佳治疗提供指导。关于决策的数据有限。使用矫形器进行保守治疗可能导致半脱位和不稳定,需要进一步治疗。并非所有情况下都需要手术,因为许多这些损伤可以在没有手术干预的情况下愈合。
回顾了在一家机构治疗的 5 年内所有颈椎骨折的病例。进一步评估了椎弓根骨折病例,并确定了 40 例经手术或不经手术治疗的病例。收集了就诊史、神经检查、影像学发现、合并症、治疗方法、并发症发生率和住院时间的数据。根据计算机断层扫描对骨折进行分类。还收集了与损伤相关的信息。通过术后 2、6 和 12 周以及损伤后 6 个月的普通 X 线片和计算机断层扫描评估骨折愈合率和骨折移位。主要结果是在没有进行性畸形(即滑脱、后凸)和需要进一步手术的情况下,无论采用何种方法,骨折均愈合。
26 例患者接受保守治疗,14 例患者接受手术治疗。两组在受伤总节段数(P = 0.9)或损伤严重程度评分(P = 0.5)方面无统计学差异。神经功能完整的患者更有可能接受保守治疗(88%对 29%;P = 0.0004),而脊髓损伤的患者更有可能接受手术固定(35%对 0%;P = 0.0004)。手术组患者的住院时间有显著延长的趋势(10.6 天对 5.5 天;P = 0.07)。根据我们的分类系统,最常见的骨折类型是单一线性水平骨折,占 68%(40 例中的 27 例)。垂直分裂椎弓根骨折占 28%(40 例中的 11 例),双一线性水平骨折占 5%(40 例中的 2 例)。保守治疗后进行性滑脱的发生率明显高于手术治疗组(31%对 0%;P = 0.03),尤其是与粉碎性侧块或半脱位或两者同时存在时。
本研究描述并分类了独特的颈椎椎弓根骨折和相关损伤。我们的发现表明,与保守治疗相比,手术治疗可使这些损伤获得明确的稳定性,特别是对于与粉碎性侧块或初始移位骨折相关的椎弓根骨折。然而,无移位的垂直分裂椎弓根骨折和单纯的单一线性水平骨折可能不需要手术治疗,也不会发生进一步的不稳定。需要更大的前瞻性研究来证实这些发现。