Laboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St, bl. 103A, BG-1113 Sofia, Bulgaria.
Laboratory of Polymeric and Composite Materials, Center of Innovation and Research in Materials and Polymers (CIRMAP), University of Mons - UMONS, Place du Parc 20, B-7000 Mons, Belgium.
Mater Sci Eng C Mater Biol Appl. 2014 Aug 1;41:119-26. doi: 10.1016/j.msec.2014.04.043. Epub 2014 Apr 28.
For the first time the preparation of defect-free fibers from immiscible blends of high molar mass poly(lactic acid) (PLA) and poly(butylene succinate) (PBS) in the whole range of the polyester weight ratios is shown. Electrospinning using the solvent-nonsolvent approach proved most appropriate. Moreover, electrospinning revealed crucial for the obtaining of PLA/PBS materials maintaining integrity. DSC and XRD analyses attested for a plasticizing effect and for increased PLA crystallinity at PBS addition to PLA. The mechanical properties of the PLA/PBS mats were controlled by the alignment of the fibers and changed from plastic to brittle materials upon increasing the PBS content. Drug loading and tests against pathogenic microorganisms suggested that the obtained mats can find application as antibacterial fibrous materials.
首次展示了在聚酯重量比的整个范围内，由高摩尔质量聚乳酸（PLA）和聚丁二酸丁二醇酯（PBS）的不混溶共混物制备无缺陷纤维。使用溶剂-非溶剂方法的静电纺丝被证明是最合适的。此外，静电纺丝对于获得保持完整性的 PLA/PBS 材料至关重要。DSC 和 XRD 分析证明了在添加 PBS 时对 PLA 具有增塑作用和增加 PLA 结晶度的作用。PLA/PBS 垫的机械性能受纤维的取向控制，并随着 PBS 含量的增加从塑性材料变为脆性材料。药物负载和对致病微生物的测试表明，所得到的垫可以用作抗菌纤维材料。
