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[阿苯达唑治疗肝和腹腔内包虫病]

[Albendazole in the treatment of hepatic and intra-abdominal hydatidosis].

作者信息

Vildósola H, Sanchéz L, Espinoza R

出版信息

Rev Gastroenterol Peru. 1989;9(1):17-23.

PMID:2490972
Abstract

Albendazole, in doses of 10 mg/kg/day for 28 days with 14 days rest periods between series and series, with a minimum of 3 and a maximum 6 series was administered to 16 patients, 13 women and 3 men, with hepatic and/or of the abdominal cavity hydatid cysts. Clinical, immunological and ultrasonographic criterion were used to evaluate the response, obtaining the following results: complete cure in 6 patients (37.5%), improvement in 7 patients (43.7%) and without change in 3 (18.7%). Drug was tolerated, occurring only one case of reversible total alopecia. There were not abnormalities in liver and renal function tests or in the haematological indices. As conclusion, Albendazole is a good therapeutic alternative in cases of inoperable or multiple hydatid cysts.

摘要

对16例患有肝和/或腹腔包虫囊肿的患者(13名女性和3名男性)给予阿苯达唑,剂量为10mg/kg/天,持续28天,系列疗程之间休息14天,最少3个系列疗程,最多6个系列疗程。采用临床、免疫学和超声标准评估疗效,结果如下:6例(37.5%)完全治愈,7例(43.7%)病情改善,3例(18.7%)无变化。药物耐受性良好,仅出现1例可逆性全秃。肝肾功能检查和血液学指标均无异常。结论是,对于无法手术或多发的包虫囊肿病例,阿苯达唑是一种很好的治疗选择。

相似文献

1
[Albendazole in the treatment of hepatic and intra-abdominal hydatidosis].[阿苯达唑治疗肝和腹腔内包虫病]
Rev Gastroenterol Peru. 1989;9(1):17-23.
2
[Albendazole for the treatment of hepatic and intra-abdominal hydatidosis].阿苯达唑治疗肝及腹腔包虫病
Rev Gastroenterol Peru. 1989;9(1):17-23.
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Observations on clinical efficacy of albendazole emulsion in 264 cases of hepatic cystic echinococcosis.阿苯达唑乳剂治疗264例肝囊型包虫病的临床疗效观察
Parasitol Int. 2004 Mar;53(1):3-10. doi: 10.1016/j.parint.2003.09.015.
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[Treatment of intra-abdominal hydatidosis with albendazole].[阿苯达唑治疗腹腔内包虫病]
Gastroenterol Hepatol. 1996 Dec;19(10):542-3.
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[Treatment of hydatidosis with albendazol].[阿苯达唑治疗包虫病]
Ugeskr Laeger. 1989 Oct 23;151(43):2791-4.
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Dual treatment of albendazole in hepatic hydatidosis: New therapeutic modality in 52 cases.阿苯达唑双重治疗肝包虫病:52例患者的新治疗模式
J Gastroenterol Hepatol. 2005 Mar;20(3):421-5. doi: 10.1111/j.1440-1746.2004.03535.x.
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[Poor results of treatment of echinococcosis with albendazole in 7 patients].7例棘球蚴病患者使用阿苯达唑治疗的不良结果
Ned Tijdschr Geneeskd. 1994 Feb 26;138(9):460-3.
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[Echinococcosis/hydatidosis in children: combined medical and surgical treatment].[儿童棘球蚴病/包虫病:药物与手术联合治疗]
Parassitologia. 1994 Dec;36(3):243-9.
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[Efficacy of low-dose albendazole therapy in hydatic liver disease: a case report].[小剂量阿苯达唑治疗肝包虫病的疗效:病例报告]
Pol Merkur Lekarski. 1999 Jul;7(37):23-4.
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The effect of albendazole on the prevention of secondary hydatidosis.阿苯达唑对预防继发性包虫病的作用。
Hepatogastroenterology. 2000 Jan-Feb;47(31):247-50.

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