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[阿苯达唑治疗肝和腹腔内包虫病]

[Albendazole in the treatment of hepatic and intra-abdominal hydatidosis].

作者信息

Vildósola H, Sanchéz L, Espinoza R

出版信息

Rev Gastroenterol Peru. 1989;9(1):17-23.

PMID:2490972
Abstract

Albendazole, in doses of 10 mg/kg/day for 28 days with 14 days rest periods between series and series, with a minimum of 3 and a maximum 6 series was administered to 16 patients, 13 women and 3 men, with hepatic and/or of the abdominal cavity hydatid cysts. Clinical, immunological and ultrasonographic criterion were used to evaluate the response, obtaining the following results: complete cure in 6 patients (37.5%), improvement in 7 patients (43.7%) and without change in 3 (18.7%). Drug was tolerated, occurring only one case of reversible total alopecia. There were not abnormalities in liver and renal function tests or in the haematological indices. As conclusion, Albendazole is a good therapeutic alternative in cases of inoperable or multiple hydatid cysts.

摘要

对16例患有肝和/或腹腔包虫囊肿的患者(13名女性和3名男性)给予阿苯达唑,剂量为10mg/kg/天,持续28天,系列疗程之间休息14天,最少3个系列疗程,最多6个系列疗程。采用临床、免疫学和超声标准评估疗效,结果如下:6例(37.5%)完全治愈,7例(43.7%)病情改善,3例(18.7%)无变化。药物耐受性良好,仅出现1例可逆性全秃。肝肾功能检查和血液学指标均无异常。结论是,对于无法手术或多发的包虫囊肿病例,阿苯达唑是一种很好的治疗选择。

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