Vildósola Gonzales H, Sanchéz L, Espinoza R
Departamento de Medicina, Facultad de Medicina, Universidad Nacional Mayor de San Marcos.
Rev Gastroenterol Peru. 1989;9(1):17-23.
Albendazole, in doses of 10mg/kg/day for 28 days with 14 days rest periods between series and series, with a minimum of 3 and a maximum 6 series was administered to 16 patients, 13 women and 3 men, with hepatic and/or of the abdominal cavity hidatid cystes. Clinical, immunological and ultrasonographic criterion were used to evaluate the response, obtaining the following results: complete cure in 6 patients (37.5%), improvement in 7 patients (43.7%) and without change in 3 (18.7%). Drug was tolerated, occurring only one case of reversible total alopecia. There were not abnormalities in liver and renal function tests or in the haematological indices. As conclusion, Albendazole is a good therapeutic alternative in cases of inoperable or multiple hydatid cysts.
对16例患有肝和/或腹腔包虫囊肿的患者(13名女性和3名男性)给予阿苯达唑,剂量为10mg/kg/天,持续28天,系列疗程之间休息14天,最少3个系列疗程,最多6个系列疗程。采用临床、免疫学和超声检查标准评估疗效,结果如下:6例(37.5%)完全治愈,7例(43.7%)病情改善,3例(18.7%)无变化。药物耐受性良好,仅出现1例可逆性全秃。肝肾功能检查和血液学指标均无异常。结论是,阿苯达唑是治疗无法手术或多发性包虫囊肿病例的良好治疗选择。