Durán Gema M, Plata María R, Zougagh Mohammed, Contento Ana M, Ríos Ángel
Department of Analytical Chemistry and Food Technology, University of Castilla-La Mancha, Avd. Camilo José Cela, s/n, E-13004 Ciudad Real, Spain; IRICA (Regional Institute of Applied Scientific Research), Av. Camilo José Cela, s/n, E-13004 Ciudad Real, Spain.
IRICA (Regional Institute of Applied Scientific Research), Av. Camilo José Cela, s/n, E-13004 Ciudad Real, Spain; Albacete Science and Technology Park, E-02006 Albacete, Spain.
J Colloid Interface Sci. 2014 Aug 15;428:235-41. doi: 10.1016/j.jcis.2014.04.050. Epub 2014 May 2.
A simple and fast procedure for water solubilization of CdSe/ZnS quantum dots (QDs) using microwave irradiation (MW) has been optimized. The CdSe/ZnS QDs were synthesized in organic media and water solubilization was achieved by replacing the initial hydrophobic ligands (TOPO and TOP) with hydrophilic heterobifunctional thiol ligands, such as L-cysteine (L-Cys), 3-mercaptopropionic acid (3-MPA) and cysteamine (CTAM). The use of MW irradiation allowed carrying out the modification of the surface thiol of QDs in a simple and fast way (only 40 s was required). Different optimization studies based on activation-time, irradiation-time, concentration of ligands, pH and lifetime fluorescent properties were carried out in order to obtain the best results for the solubilization of QDs. By the proposed method, the resulting water-soluble QDs exhibit a strong fluorescence emission at about 590 nm, with a high and reproducible photostability and acceptable yields. With the aim of contributing to exploiting the advantages of synthetized QDs from an analytical point of view, the different behavior with sulfonylurea herbicides (SUHs) were studied.
一种使用微波辐射（MW）使CdSe/ZnS量子点（QDs）水溶的简单快速方法已得到优化。CdSe/ZnS量子点在有机介质中合成，通过用亲水性异双功能硫醇配体（如L-半胱氨酸（L-Cys）、3-巯基丙酸（3-MPA）和半胱胺（CTAM））取代初始疏水性配体（TOPO和TOP）实现水溶。使用微波辐射能够以简单快速的方式（仅需40秒）对量子点的表面硫醇进行修饰。基于活化时间、辐射时间、配体浓度、pH值和荧光寿命特性开展了不同的优化研究，以便获得量子点水溶的最佳结果。通过所提出的方法，所得水溶性量子点在约590nm处呈现出强烈的荧光发射，具有高且可重现的光稳定性和可接受的产率。为了从分析角度有助于利用合成量子点的优势，研究了其与磺酰脲类除草剂（SUHs）的不同行为。
