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针对有阻塞性睡眠呼吸暂停综合征风险的孕妇,对呼吸暂停风险评估系统(ARES)设备与实验室多导睡眠图进行验证。

Validation of the Apnea Risk Evaluation System (ARES) device against laboratory polysomnography in pregnant women at risk for obstructive sleep apnea syndrome.

作者信息

Sharkey Katherine M, Waters Kelly, Millman Richard P, Moore Robin, Martin Susan M, Bourjeily Ghada

机构信息

Department of Medicine, Alpert Medical School of Brown University, Providence, RI ; Department of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence, RI ; Sleep Disorders Center of Lifespan Hospitals, Providence, RI.

Department of Neurology, Alpert Medical School of Brown University, Providence, RI.

出版信息

J Clin Sleep Med. 2014 May 15;10(5):497-502. doi: 10.5664/jcsm.3694.

DOI:10.5664/jcsm.3694
PMID:24910550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4046363/
Abstract

STUDY OBJECTIVE

To assess the validity of using the Apnea Risk Evaluation System (ARES) Unicorder for detecting obstructive sleep apnea (OSA) in pregnant women.

METHODS

Sixteen pregnant women, mean age (SD) = 29.8 (5.4) years, average gestational age (SD) = 28.6 (6.3) weeks, mean body mass index (SD) = 44.7 (6.9) kg/m(2) with signs and symptoms of OSA wore the ARES Unicorder during one night of laboratory polysomnography (PSG). PSG was scored according to AASM 2007 criteria, and PSG AHI and RDI were compared to the ARES 1%, 3%, and 4% AHIs calculated with the ARES propriety software.

RESULTS

Median PSG AHI and PSG RDI were 3.1 and 10.3 events/h of sleep, respectively. Six women had a PSG AHI ≥ 5 events/h of sleep and 11 had a PSG RDI ≥ 5 events/h of sleep. PSG AHI and RDI were strongly correlated with the ARES AHI measures. When compared with polysomnographic diagnosis of OSA, the ARES 3% algorithm provided the best balance between sensitivity (1.0 for PSG AHI, 0.91 for PSG RDI) and specificity (0.5 for PSG AHI, 0.8 for PSG RDI) for detecting sleep disordered breathing in our sample.

CONCLUSIONS

The ARES Unicorder demonstrated reasonable consistency with PSG for diagnosing OSA in this small, heterogeneous sample of obese pregnant women.

摘要

研究目的

评估使用呼吸暂停风险评估系统(ARES)记录仪检测孕妇阻塞性睡眠呼吸暂停(OSA)的有效性。

方法

16名平均年龄(标准差)=29.8(5.4)岁、平均孕周(标准差)=28.6(6.3)周、平均体重指数(标准差)=44.7(6.9)kg/m²且有OSA体征和症状的孕妇在一晚的实验室多导睡眠图(PSG)监测期间佩戴ARES记录仪。PSG根据美国睡眠医学会(AASM)2007年标准进行评分,并将PSG的呼吸暂停低通气指数(AHI)和呼吸紊乱指数(RDI)与使用ARES专用软件计算出的ARES的1%、3%和4%的AHI进行比较。

结果

PSG的AHI中位数和RDI中位数分别为每小时睡眠3.1次和10.3次事件。6名女性的PSG AHI≥每小时睡眠5次事件,11名女性的PSG RDI≥每小时睡眠5次事件。PSG的AHI和RDI与ARES的AHI测量值高度相关。与OSA的多导睡眠图诊断相比,ARES的3%算法在检测我们样本中的睡眠呼吸障碍时,在敏感性(PSG AHI为1.0,PSG RDI为0.91)和特异性(PSG AHI为0.5,PSG RDI为0.8)之间提供了最佳平衡。

结论

在这个由肥胖孕妇组成的小型异质样本中,ARES记录仪在诊断OSA方面与PSG表现出合理的一致性。

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