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意大利撒丁岛一个长寿社区的差异死亡率:一项队列分析。

Differential mortality in a long-living community in Sardinia (Italy): a cohort analysis.

作者信息

Salaris Luisa

机构信息

Department of Social Sciences and Institutions,University of Cagliari,Italy.

出版信息

J Biosoc Sci. 2015 Jul;47(4):521-35. doi: 10.1017/S0021932014000224. Epub 2014 Jun 9.

Abstract

The majority of studies on longevity in Sardinia point to an exceptional level of longevity, particularly for males, in this region of Italy. This study used individual data, considering selected groups of individuals such as centenarians, or focusing on cohorts of newborns in a large time period, that have previously been treated as a single group. An analysis on decennial birth cohorts from 1872 to 1911 in a selected village located in the Blue Zone area of longevity in Sardinia was used to gain insight into sex differentials in mortality in this area of high longevity and to separate differences between cohorts' experiences, considering the possible role of significant events in determining differential mortality among them. The results show that there is not a secular trend in survival in the birth cohorts under study, but rather that several points of mortality convergence and crossover occur, which make the estimates derived from conventional sensitivity tests of survival curves unreliable. Differences among birth cohorts' experiences are more marked among the male population and at early adult ages. External events are shown to play a relevant role in mortality variations, despite not having an impact on the ageing process. The results highlight that, although there are not statistically significant differences between the two sexes, the male population is exposed to a higher risk of death and proves to be more vulnerable to external changes. This suggests that extreme contextual conditions, both favourable and unfavourable, may significantly affect the mortality trajectories of a population.

摘要

大多数关于撒丁岛长寿情况的研究表明,在意大利的这个地区存在着极高的长寿水平,尤其是男性。本研究使用了个体数据,考虑了特定的个体群体,如百岁老人,或者关注在较长时间段内的新生儿队列,这些此前都被视为一个单一群体。对撒丁岛长寿蓝区选定村庄中1872年至1911年每十年出生队列的分析,旨在深入了解这个高长寿地区的死亡率性别差异,并区分不同队列经历之间的差异,同时考虑重大事件在决定他们之间死亡率差异方面可能发挥的作用。结果表明,在所研究的出生队列中,生存情况不存在长期趋势,而是出现了几个死亡率趋同和交叉点,这使得从传统生存曲线敏感性测试得出的估计结果不可靠。不同出生队列经历之间的差异在男性群体和成年早期更为明显。外部事件在死亡率变化中显示出发挥了相关作用,尽管对衰老过程没有影响。结果突出表明,尽管两性之间没有统计学上的显著差异,但男性群体面临更高的死亡风险,并且被证明更容易受到外部变化的影响。这表明,无论是有利还是不利的极端环境条件,都可能显著影响一个人群的死亡轨迹。

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