Jakobiec Frederick A, Rashid Alia, Massoud Vicky, Fay Aaron
*David G. Cogan Laboratory of Ophthalmic Pathology; †Harvard Medical School; and ‡Ophthalmic Plastic Surgery Service, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, U.S.A.
Ophthalmic Plast Reconstr Surg. 2016 Mar-Apr;32(2):e32-4. doi: 10.1097/IOP.0000000000000208.
Secondary complications in an anophthalmic socket can include late appearing shrinkage due to scarring and squamous cell carcinoma. This article reports a 51-year-old man who 27 years after an enucleation developed an inability to retain his ocular prosthesis due to an acquired multilobular fleshy mass in his inferior fornix. The patient had worn his prosthesis without removal for years at a time. Microscopic evaluation of the excised lesion disclosed a pseudoadenomatous (pseudoglandular) hyperplasia of the conjunctival epithelium with myriad goblet cells and accompanying chronic inflammation. In cross section, these structures microscopically resembled an adenoma but were found to display multifocal origins from the surface epithelium resembling exaggerated pseudoglands of Henle. Simple excision without recurrence 6 months later has permitted a new prosthesis to be comfortably worn with stability.
无眼球眼眶的继发性并发症可能包括因瘢痕形成导致的晚期萎缩和鳞状细胞癌。本文报道了一名51岁男性，在眼球摘除术后27年，由于下穹窿部出现一个后天性多叶状肉质肿物，导致无法佩戴义眼。该患者一次佩戴义眼多年未取出。对切除病变的显微镜检查显示结膜上皮呈假腺瘤样（假腺性）增生，有大量杯状细胞，并伴有慢性炎症。在横切面上，这些结构在显微镜下类似腺瘤，但发现它们起源于表面上皮的多灶性病变，类似于扩大的亨勒假腺。简单切除后6个月未复发，使患者能够舒适且稳定地佩戴新的义眼。
