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眼眶癌的发病会是义眼导致的吗?

Can the onset of orbital cancer be the result of a prosthetic eye?

作者信息

Croce A, Mastronardi V, Laus M, Festa Kotelnikova E

机构信息

ENT Department, University "G. d'Annunzio" of Chieti-Pescara, Hospital "SS Annunziata", Chieti, Italy.

出版信息

Acta Otorhinolaryngol Ital. 2017 Dec;37(6):519-522. doi: 10.14639/0392-100X-1043.

DOI:10.14639/0392-100X-1043
PMID:28530256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5782431/
Abstract

Orbital exenteration is a disfiguring procedure performed for unresponsive orbital infections and control of recurrent benign tumours and malignancies arising from the eyelids (basal cell carcinoma, squamous cell carcinoma, conjunctival malignant melanoma), lachrymal glands (adenoid cystic carcinoma) or surrounding sinuses. In extremely rare cases the use of a prosthetic eye after enucleation can lead to anophthalmic socket tumours. We report the case of a 54-year-old man who had left eye enucleation due to recurring events of retinal detachment and who developed an invasive fast growing epidermoid carcinoma 30 years later. We review the literature to evaluate the rarity of the occurrence, time of onset after enucleation, treatments and outcomes. Our case illustrates the management of the pathology and emphasises the necessity of careful examination of the anophthalmic socket and the ocular prosthesis to identify any irregularities or damage on its surface even after exenteration that is not performed for malignant disease. Long-term follow up is necessary because this tumour could occur at long time periods after enucleation.

摘要

眼眶内容剜除术是一种毁容性手术,用于治疗难治性眼眶感染以及控制源自眼睑(基底细胞癌、鳞状细胞癌、结膜恶性黑色素瘤)、泪腺(腺样囊性癌)或周围鼻窦的复发性良性肿瘤和恶性肿瘤。在极为罕见的情况下,眼球摘除术后使用义眼可能会导致无眼球眼眶肿瘤。我们报告了一例54岁男性病例,该患者因视网膜脱离反复发作而摘除了左眼,30年后发生了侵袭性快速生长的表皮样癌。我们回顾文献以评估该病例发生的罕见性、眼球摘除术后的发病时间、治疗方法及结果。我们的病例说明了该病理情况的处理,并强调即使在非因恶性疾病而进行的眼眶内容剜除术后,也有必要仔细检查无眼球眼眶和眼假体,以识别其表面的任何不规则或损伤。长期随访是必要的,因为这种肿瘤可能在眼球摘除术后很长时间才出现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e306/5782431/b4f94c5f8ff2/0392-100X-37-519-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e306/5782431/b4f94c5f8ff2/0392-100X-37-519-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e306/5782431/b4f94c5f8ff2/0392-100X-37-519-g001.jpg

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本文引用的文献

1
A 12-year retrospective survey of management of patients with malignant neoplasms in the orbital cavity in a brazilian cancer hospital.巴西一家癌症医院对眼眶恶性肿瘤患者治疗情况的12年回顾性调查。
Open Dent J. 2013 Oct 31;7:140-5. doi: 10.2174/1874210601307010140. eCollection 2013.
2
Ocular surface squamous neoplasia in an anophthalmic socket 60 years after enucleation.眼窝摘除 60 年后的眼窝内眼表面鳞状上皮肿瘤。
Surv Ophthalmol. 2011 Nov-Dec;56(6):539-43. doi: 10.1016/j.survophthal.2011.06.005.
3
Orbital exenteration in elderly patients: personal experience.
老年患者的眼眶内容剜除术:个人经验
Acta Otorhinolaryngol Ital. 2008 Aug;28(4):193-9.
4
Conjunctival cytologic features in anophthalmic patients wearing an ocular prosthesis.佩戴义眼的无眼球患者的结膜细胞学特征。
Ophthalmic Plast Reconstr Surg. 2008 Jul-Aug;24(4):290-5. doi: 10.1097/IOP.0b013e3181788dff.
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The esthetics of orbital exenteration.
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Survival after malignant tumors of the orbit and periorbit treated by exenteration.经眼眶内容剜除术治疗的眼眶及眶周恶性肿瘤患者的生存率。
Acta Ophthalmol Scand. 1999 Jun;77(3):326-30. doi: 10.1034/j.1600-0420.1999.770316.x.