Pazos M R, Reig R, Sanz P, Nogue S, Boix D, Palomar M, Tenorio L, Corbella J
An Med Interna. 1989 Mar;6(3):151-3.
3 cases of suicide due to ingestion of 150, 200 and 4 gr. of paraquat, respectively, are presented. Two of them were brothers and agricultural industrialists, the other one was a farmer. The first two cases died 16 and 10 hours after intake. The farmer died 21 days after ingestion. All of them had progressive hypoxemia and renal failure the two brothers had heart conduction system glycemia (23 mg/dl) a few hours after ingestion. The postmortem study showed edema, hemorrhage and congestion of the lungs, alveolitis, fibrosis and lobar atelectasia; renal tubular necrosis adrenal necrosis; colestasia; hepatic steatosis focal miocarditis. The clinical evolution, particularly short in the first two patients, is commented on, as well as the post-mortem findings, comparing them with those described in the literature. Finally, due to the high toxicity of this herbicide, we insist in prompt transport to herbicide, we insist in prompt transport to the hospital in order to apply early treatment.
本文报告了3例百草枯中毒自杀病例，摄入量分别为150克、200克和4克。其中2例为兄弟俩，是农业实业家，另1例是农民。前2例分别在摄入百草枯16小时和10小时后死亡。农民在摄入后21天死亡。他们均出现进行性低氧血症和肾衰竭，两兄弟在摄入后数小时出现心脏传导系统血糖异常（23毫克/分升）。尸检显示肺部水肿、出血和充血、肺泡炎、纤维化和肺叶不张；肾小管坏死、肾上腺坏死；胆汁淤积；肝脂肪变性、局灶性心肌炎。对前两名患者特别短的临床病程以及尸检结果进行了评论，并与文献中描述的结果进行了比较。最后，由于这种除草剂的高毒性，我们强调应迅速将患者送往医院以便尽早治疗。
