Inaji Motoki, Maehara Taketoshi
Nihon Rinsho. 2014 May;72(5):827-33.
Morphological imaging tools, such as MRI and CT, are now recommended to be carried out in all patients with epilepsy. However, no lesion is sometimes visualized on MRI in location related epilepsy patients, further neuroimaging tools are required for presurgical evaluation. In order to identify epileptic focus, PET, SPECT and MEG have been proposed as clinically relevant tools. These are useful and reliable examinations in clinical routine as well as for research purpose. Their ability to image in vivo changes in brain biochemistry has provided valuable insights into the epileptogenesis, seizure propagation and termination. In future, further progression in the sensitivity and spatial resolution of each examination will probably increase the clinical role in the assessment of patients with epilepsy.