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用于老年抑郁症和认知障碍的天然产物与补充剂:研究评估

Natural products and supplements for geriatric depression and cognitive disorders: an evaluation of the research.

作者信息

Varteresian Taya, Lavretsky Helen

机构信息

VA Long Beach Health Care System, 5901 East 7th Street, Long Beach, CA, 90822, USA,

出版信息

Curr Psychiatry Rep. 2014 Aug;16(8):456. doi: 10.1007/s11920-014-0456-x.

DOI:10.1007/s11920-014-0456-x
PMID:24912606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4110105/
Abstract

Numerous geriatric patients are using Complementary and Alternative Medicine (CAM) for late-life mood and cognitive disorders. Natural products and supplements are a common CAM intervention which have risks and benefits of which patients should be appropriately advised. The data for omega-3 fatty acids, ginkgo biloba, SAMe, St John's wort, B vitamins and vitamin D, huperzine, caprylidene, and coconut oil will be evaluated. Since the evidence basis for natural products and supplements is limited, especially for the geriatric population, studies involving the general adult population are included to infer effects in the aging population. Despite the data available, more rigorous studies with larger sample sizes over longer periods of time are still needed. Regardless of a physician's preference to recommend various natural supplements and products, a physician could protect their patients by having an understanding of the side effects and indications for various natural products.

摘要

许多老年患者正在使用补充和替代医学(CAM)来治疗晚年的情绪和认知障碍。天然产品和补充剂是常见的CAM干预措施,它们有风险也有好处,应该适当地告知患者。将评估ω-3脂肪酸、银杏叶、S-腺苷甲硫氨酸、圣约翰草、B族维生素和维生素D、石杉碱、辛弗林和椰子油的数据。由于天然产品和补充剂的证据基础有限,尤其是老年人群,因此纳入了涉及一般成年人群的研究,以推断对老年人群的影响。尽管有现有数据,但仍需要进行更严格、样本量更大、时间更长的研究。无论医生是否倾向于推荐各种天然补充剂和产品,医生都可以通过了解各种天然产品的副作用和适应症来保护他们的患者。

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