Eyre Harris, Baune Bernhard, Lavretsky Helen
Discipline of Psychiatry, University of Adelaide, 55 Frome Road, Adelaide, South Australia 5005, Australia; Semel Institute for Neuroscience, University of California, Los Angeles, 760 Westwood Boulevard, Los Angeles, CA 90095, USA.
Discipline of Psychiatry, University of Adelaide, 55 Frome Road, Adelaide, South Australia 5005, Australia.
Psychiatr Clin North Am. 2015 Sep;38(3):495-514. doi: 10.1016/j.psc.2015.05.002. Epub 2015 Jun 26.
The world population is aging at a rate unprecedented in human history, placing substantial pressure on health systems across the world along with concurrent rises in chronic diseases. In particular, rates of cognitive disorders and late-life affective disorders are expected to increase. In tandem with aging, there are robust predictions suggesting that rates of age-related cognitive decline and dementia, and geriatric depression, will increase, with serious consequences. Clearly innovative prevention and treatment strategies are needed. This article reviews the latest promising clinical advances that hold promise for assisting the prevention and treatment of depression, cognitive decline, and dementia.
世界人口正在以前所未有的速度老龄化,这给世界各地的卫生系统带来了巨大压力,与此同时慢性病的发病率也在上升。特别是,认知障碍和晚年情感障碍的发病率预计将会增加。随着老龄化的加剧,有可靠的预测表明,与年龄相关的认知衰退、痴呆症以及老年抑郁症的发病率将会上升,并带来严重后果。显然,需要创新的预防和治疗策略。本文回顾了最新的有前景的临床进展,这些进展有望辅助抑郁症、认知衰退和痴呆症的预防与治疗。