Mogica-Mogica Juan Dios, Gómez-López Víctor Manuel
Servicio de Alergología e Inmunología Clínica, Hospital General Regional núm. 6, Instituto Mexicano del Seguro Social. Escuela de Medicina "Dr. José Sierra Flores", Universidad del Noreste. Ciudad Madero, Tamaulipas, México.
Rev Alerg Mex. 2013 Oct-Dec;60(4):161-3.
Chronic urticaria is characterized by swelling and itchy hives presenting remissions and exacerbations, for six weeks or more, which may or may not be accompanied by angioedema. Helicobacter pylori infection has been associated with various diseases among them chronic urticaria.
To determine the association between H. pylori infection and allergic and non-allergic chronic urticaria.
We conducted a retrospective, observational and cross-sectional study which included 82 patients of both sexes with a diagnosis of chronic urticaria, aged between 2 and 75 years. Total serum IgE and IgG anti-H. pylori were measured in all participants. Statistical analysis was performed using the chi-squared test with 0.05 significance.
A total of 82 patients, 33 males and 49 females, with a mean age of 36.9 years were studied. H. pylori seropositivity was in 65.2% of allergic patients and 34.8% of non-allergic patients (p = 0.148).
We found no association between chronic allergic urticaria and H. pylori infection.
慢性荨麻疹的特征是出现肿胀和瘙痒性风团，缓解与加重交替出现，持续六周或更长时间，可能伴有或不伴有血管性水肿。幽门螺杆菌感染与多种疾病有关，其中包括慢性荨麻疹。
确定幽门螺杆菌感染与过敏性和非过敏性慢性荨麻疹之间的关联。
我们进行了一项回顾性、观察性横断面研究，纳入了82例年龄在2至75岁之间、诊断为慢性荨麻疹的男女患者。对所有参与者检测血清总IgE和抗幽门螺杆菌IgG。采用卡方检验进行统计分析，显著性水平为0.05。
共研究了82例患者，其中男性33例，女性49例，平均年龄36.9岁。过敏性患者中幽门螺杆菌血清阳性率为65.2%，非过敏性患者中为34.8%（p = 0.148）。
我们发现慢性过敏性荨麻疹与幽门螺杆菌感染之间无关联。
