School of Medicine, Deakin University, Geelong, Australia.
School of Medicine, Deakin University, Geelong, Australia; Department of Psychiatry, The University of Melbourne, Parkville, Australia.
J Clin Densitom. 2015 Jan-Mar;18(1):13-6. doi: 10.1016/j.jocd.2014.04.123. Epub 2014 Jun 7.
Osteoporosis is a major health concern, estimated to affect millions worldwide. Bone mineral density (BMD) assessment is not practical for many large-scale epidemiological studies resulting in the reliance of self-report methods to ascertain diagnostic information. The aim of the study was to assess the validity of self-reported diagnosis of osteoporosis in a population-based study. This study examined data collected from 906 men and 843 women participating in the Geelong Osteoporosis Study. Osteoporosis was self-reported and compared against results of BMD scans of the hip and spine. Validity was examined by calculating sensitivity, specificity, positive predictive value, negative predictive value, and kappa statistic. Osteoporosis was self-reported by 118 (6.7%) participants and identified using BMD results for 64 (3.7%) participants. Specificity and negative predictive value were good (95.1% and 96.0%, respectively), whereas sensitivity and positive predictive value were poor (35.9% and 31.4%, respectively). The overall level of agreement (kappa) was 0.29. The results changed only slightly when we included participants with osteopenia and adult fracture as osteoporotic. Reliance on self-report methods to ascertain osteoporosis status is not recommended.
骨质疏松症是一个主要的健康问题，据估计影响了全球数百万人。由于许多大规模的流行病学研究都不实用骨矿物质密度 (BMD) 评估，因此依赖于自我报告方法来确定诊断信息。本研究旨在评估基于人群的研究中自我报告的骨质疏松症诊断的有效性。该研究检查了参与 Geelong 骨质疏松症研究的 906 名男性和 843 名女性的数据。骨质疏松症是自我报告的，并与髋部和脊柱的 BMD 扫描结果进行了比较。通过计算敏感性、特异性、阳性预测值、阴性预测值和kappa 统计量来检查有效性。118 名（6.7%）参与者自我报告了骨质疏松症，并通过 64 名（3.7%）参与者的 BMD 结果确定了骨质疏松症。特异性和阴性预测值良好（分别为 95.1%和 96.0%），而敏感性和阳性预测值较差（分别为 35.9%和 31.4%）。总体一致性（kappa）为 0.29。当我们将骨质疏松症和成人骨折的参与者包括在内时，结果变化很小。不建议依赖自我报告方法来确定骨质疏松症的状况。
