Rozenberg Dmitry, Shapera Shane
Can Respir J. 2014 May-Jun;21(3):e52-4. doi: 10.1155/2014/593430.
Caplan syndrome is a rare entity that is specific to rheumatoid arthritis and presents with multiple, well-defined necrotic nodules in patients with occupational dust exposure. The present report describes a case of Caplan syndrome involving a 71-year-old man with a known diagnosis of seropositive rheumatoid arthritis who presented to the authors' centre with a five-year history of multiple, bilateral cavitary lung nodules with mild dyspnea on exertion. He was an ex-smoker (30 pack-years) and had previously worked with silica. The case highlights the clinical, radiological and pathological features of this syndrome and outlines the importance of considering a broad differential in the management of pulmonary nodules, especially in patients with rheumatoid arthritis.
卡普兰综合征是一种类风湿关节炎特有的罕见病症，在有职业性粉尘接触史的患者中表现为多个边界清晰的坏死结节。本报告描述了一例卡普兰综合征病例，患者为一名71岁男性，已知患有血清阳性类风湿关节炎，因有5年双侧多发空洞性肺结节病史且活动时轻度呼吸困难前来作者所在中心就诊。他既往吸烟（30包年），曾从事二氧化硅相关工作。该病例突出了此综合征的临床、放射学及病理学特征，并概述了在处理肺结节时，尤其是类风湿关节炎患者中考虑广泛鉴别诊断的重要性。
