Lee Hae-Jeung, Cho Jang-ik, Lee Hye-Seung H, Kim Cho-il, Cho Eunyoung
Department of Food & Nutrition, Eulji University, Seongnam-si, Gyeonggi-do, South Korea.
Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America.
PLoS One. 2014 Jun 10;9(6):e99085. doi: 10.1371/journal.pone.0099085. eCollection 2014.
The possible effects of dairy product intake against obesity have been suggested in animal studies; however, the association is still not well established in epidemiological studies. Few studies in Asian countries with relatively low intake of dairy products exist.
We investigated the association between dairy products and calcium intake and obesity in Korean population with relatively low intake of dairy products.
Our study population consisted of adults (n = 7173) aged 19-64 among participants of the 2007, 2008 and 2009 Korean National Health and Nutrition Examination Survey who had not made any attempt of intentional weight loss. Dietary intake data from food frequency questionnaire (FFQ) and 24-hour recall were used. Dairy products included milk and yogurt in the FFQ. Obesity was defined as BMI≥25 kg/m².
Higher frequency of dairy product intake was associated with a reduced prevalence of obesity (OR = 0.63; 95% CI = 0.45-0.89 for ≥2 times/day vs. ≤1 time/month; p for trend = 0.003) using the intake data from FFQ. Similarly, high frequency of milk or yogurt intake had an inverse association with obesity. The association between milk and yogurt intake and obesity was similar when the intake from 24-hour recall was examined. Higher calcium intake from dairy products as well as total dietary calcium intake was associated with a decreased prevalence of obesity (OR = 0.83; 95% CI = 0.71-0.98 for highest vs. lowest quintile of dairy calcium intake; p for trend = 0.02, OR = 0.78; 95% CI = 0.64-0.94 for highest vs. lowest quintile of total calcium intake; p for trend = 0.04). The associations appeared to be stronger in women than in men.
These results suggest that high consumption of dairy products is associated with a lower prevalence of obesity and that calcium in dairy products may be one of the components contributing to the association. Further longitudinal studies are warranted to replicate our findings.
动物研究表明乳制品摄入对肥胖可能有影响;然而,在流行病学研究中这种关联仍未完全确立。亚洲国家乳制品摄入量相对较低,此类研究较少。
我们在乳制品摄入量相对较低的韩国人群中,调查乳制品和钙摄入与肥胖之间的关联。
我们的研究人群包括2007、2008和2009年韩国国民健康与营养检查调查中19 - 64岁未尝试过有意减肥的成年人(n = 7173)。使用了食物频率问卷(FFQ)和24小时回顾法的饮食摄入数据。FFQ中的乳制品包括牛奶和酸奶。肥胖定义为BMI≥25 kg/m²。
使用FFQ的摄入数据,较高频率的乳制品摄入与肥胖患病率降低相关(每天≥2次与每月≤1次相比,OR = 0.63;95%CI = 0.45 - 0.89;趋势p值 = 0.003)。同样,高频率的牛奶或酸奶摄入与肥胖呈负相关。当检查24小时回顾法的摄入量时,牛奶和酸奶摄入与肥胖之间的关联相似。来自乳制品的较高钙摄入量以及总膳食钙摄入量与肥胖患病率降低相关(乳制品钙摄入量最高五分位数与最低五分位数相比,OR = 0.83;95%CI = 0.71 - 0.98;趋势p值 = 0.02,总钙摄入量最高五分位数与最低五分位数相比,OR = 0.78;95%CI = 0.64 - 0.94;趋势p值 = 0.04)。这种关联在女性中似乎比男性更强。
这些结果表明,高消费乳制品与较低的肥胖患病率相关,并且乳制品中的钙可能是促成这种关联的成分之一。有必要进行进一步的纵向研究来重复我们的发现。