Serrano Navarro S, Soriano Palao P, Sánchez Juan C, Ascaso Gimilio J F, Martínez-Valls J F, Carmena Rodríguez R
An Med Interna. 1989 May;6(5):230-4.
We studied the risk factors of coronary disease in 52 patients (46 male and 6 female) survivors of myocardial infarction (MI). We found that a group of patients under 40 years old had predominant lipid alteration (100%) being hypercholesterolemia (CT greater than or equal to 260 mg/dl), the decrease of HDL-C levels (less than or equal to 35 mg/dl) and the increase of the atherogenic index (CT/HDL-C greater than or equal to 6) being the most frequent. At the same time, we observed an important association between several risk factors, such as tobacco consumption (58.5%), sedentary life (56.1%), lipid alterations (hypercholesterolemia: 46.3%, decrease of HDL-C: 41.4%, increase of atherogenic index: 60.9%) in the group of patients under 40 years old. These data show that the alterations of lipid metabolism are risk factors frequently observed in young patients with ischemic cardiac disease.
我们研究了52例心肌梗死(MI)幸存者(46例男性和6例女性)的冠心病危险因素。我们发现,一组40岁以下的患者主要存在脂质改变(100%),即高胆固醇血症(总胆固醇[CT]大于或等于260mg/dl),高密度脂蛋白胆固醇(HDL-C)水平降低(小于或等于35mg/dl)以及致动脉粥样硬化指数升高(CT/HDL-C大于或等于6)最为常见。同时,我们观察到40岁以下患者组中几种危险因素之间存在重要关联,如吸烟(58.5%)、久坐不动的生活方式(56.1%)、脂质改变(高胆固醇血症:46.3%,HDL-C降低:41.4%,致动脉粥样硬化指数升高:60.9%)。这些数据表明,脂质代谢改变是年轻缺血性心脏病患者中常见的危险因素。