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蛋白质能量营养不良:多种疾病的风险因素。

Protein-energy malnutrition: a risk factor for various ailments.

机构信息

a National Institute of Food Science & Technology, University of Agriculture , Faisalabad , Pakistan.

出版信息

Crit Rev Food Sci Nutr. 2015;55(2):242-53. doi: 10.1080/10408398.2011.651543.

Abstract

The wheel of industrialization that spun throughout the last century resulted in urbanization coupled with modifications in lifestyles and dietary habits. However, the communities living in developing economies are facing many problems related to their diet and health. Amongst, the prevalence of nutritional problems especially protein-energy malnutrition (PEM) and micronutrients deficiencies are the rising issues. Moreover, the immunity or susceptibility to infect-parasitic diseases is also directly linked with the nutritional status of the host. Likewise, disease-related malnutrition that includes an inflammatory component is commonly observed in clinical practice thus affecting the quality of life. The PEM is treatable but early detection is a key for its appropriate management. However, controlling the menace of PEM requires an aggressive partnership between the physician and the dietitian. This review mainly attempts to describe the pathophysiology, prevalence and consequences of PEM and aims to highlight the importance of this clinical syndrome and the recent growth in our understanding of the processes behind its development. Some management strategies/remedies to overcome PEM are also the limelight of the article. In the nutshell, early recognition, prompt management, and robust follow up are critical for best outcomes in preventing and treating PEM.

摘要

上个世纪工业化的车轮带动了城市化的发展,随之而来的是生活方式和饮食习惯的改变。然而,发展中经济体的社区在饮食和健康方面面临着许多问题。其中,营养问题,特别是蛋白质-能量营养不良(PEM)和微量营养素缺乏症的流行,是日益严重的问题。此外,宿主的营养状况也直接影响其对寄生虫病的免疫力或易感性。同样,与疾病相关的营养不良,包括炎症成分,在临床实践中也很常见,从而影响生活质量。PEM 是可以治疗的,但早期发现是其适当管理的关键。然而,要控制 PEM 的威胁,需要医生和营养师之间的积极合作。本篇综述主要试图描述 PEM 的病理生理学、流行情况和后果,并旨在强调这种临床综合征的重要性,以及我们对其发展背后过程的理解的最新进展。克服 PEM 的一些管理策略/补救措施也是本文的重点。简而言之,早期识别、及时管理和有力的随访对于预防和治疗 PEM 以获得最佳结果至关重要。

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