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[慢性活动性肝炎患者的中性粒细胞趋化作用]

[Neutrophil chemotaxis in patients with chronic active hepatitis].

作者信息

Giménez López M J, Muniain Ezcurra M A, Jiménez Saenz M, Rodríguez López M D, Cuenca López L, Garrido Peralta M

出版信息

An Med Interna. 1989 Jun;6(6):305-8.

PMID:2491554
Abstract

The serum of 18 patients diagnosed as having chronic active hepatitis (CAH) was studied in order to ascertain the neutrophil motility in healthy person serum. The chemotaxis and the chemokinesis induced by the serum of the patients were lower than those obtained using a control serum. When the control serum, activated by zymosan, was added to the patients serum a decrease of chemotaxis was observed. Contrary to this, when activated serum of patients was added to the control serum, there was no alteration of chemotaxis. We concluded that serum of patients affected by CAH have an inhibitor of the motility of neutrophils.

摘要

为了确定健康人血清中的中性粒细胞运动性,对18例被诊断为慢性活动性肝炎(CAH)患者的血清进行了研究。患者血清诱导的趋化性和化学增活现象低于使用对照血清时获得的结果。当将经酵母聚糖激活的对照血清添加到患者血清中时,观察到趋化性降低。与此相反,当将患者的激活血清添加到对照血清中时,趋化性没有改变。我们得出结论,受CAH影响的患者血清中有中性粒细胞运动性的抑制剂。

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