Hidalgo M M, Avila-Campos M J, Trevisan W, Mocelin T T, Itano E N
Departamento de Odontología, Universidade Estadual de Maringá, PR, Brazil.
Arch Med Res. 1997 Winter;28(4):531-5.
The polymorphonuclear neutrophil (PMN) chemotaxis index and modulation of serum factors in 15 Brazilian periodontal patients (five localized juvenile and ten adult periodontitis) and ten healthy subjects were examined. Adult periodontitis patients showed a normal chemotaxis index, Localized juvenile periodontitis LJP patients showed diminished chemotaxis and serum cell-directed inhibitor activity. The results suggest that PMN abnormalities could not be caused by only the neutrophils themselves, but also by modulation of serum factors acting on this LJP disease.
对15名巴西牙周病患者(5例局限性青少年牙周炎和10例成人牙周炎)和10名健康受试者的多形核中性粒细胞(PMN)趋化指数及血清因子调节情况进行了检测。成人牙周炎患者的趋化指数正常,局限性青少年牙周炎(LJP)患者的趋化作用减弱,血清细胞定向抑制活性降低。结果表明,PMN异常不仅可能由中性粒细胞自身引起,还可能由作用于这种LJP疾病的血清因子调节所致。