Nagasawa Hiroyuki, Kohno Yoshinori, Yamamoto Yutaka, Kondo Masashi, Sugawara Masami, Koyama Toshinari, Terazawa Daisuke, Miura Ryosuke
Department of Neonatology, Gifu Prefectural General Medical Center, 4-6-1 Noisshiki, Gifu, 500-8717, Japan,
Pediatr Cardiol. 2014 Dec;35(8):1415-20. doi: 10.1007/s00246-014-0944-0. Epub 2014 Jun 11.
Several methods for evaluating left ventricular stroke volume (SV) in neonates using echocardiography have been reported. However, no studies on methodologic comparison of SV with three-dimensional (3D) echocardiography are available. This is the first detailed report on a methodologic comparison of SV in the early neonatal period. The study group included 70 normal neonates (35 boys and 35 girls). An iE33 echocardiograph and Q-LAB supplied by Philips Electronics were used to examine and calculate volumes. Comparisons of SV were performed using Teichholz (T), the velocity time integral (VTI), Pombo (P), modified Simpson (MS), and 3D methods with normal neonates who had no persistent ductus arteriosus less than 7 days after birth. The mean SVs were 33.7 mL/m(2) (T), 30.6 mL/m(2) (VTI), 22.0 mL/m(2) (P), 17.5 mL/m(2) (3D), and 14.9 mL/m(2) (MS) using Haycock's formula of body surface area. The stroke volumes differed significantly depending on the different methods. The correlation coefficient was highest between the MS and 3D methods. The SVs of the T and VTI methods were significantly greater than those previously reported, and it seemed inappropriate to evaluate volumes in neonates. The 3D and MS methods were appropriate for measuring SV in neonates during the early neonatal period.
已有报道称，有几种利用超声心动图评估新生儿左心室每搏输出量（SV）的方法。然而，目前尚无关于三维（3D）超声心动图测量SV的方法学比较研究。这是首篇关于新生儿早期SV方法学比较的详细报告。研究组包括70名正常新生儿（35名男婴和35名女婴）。使用飞利浦电子公司提供的iE33超声心动图仪和Q-LAB来检查和计算容积。对出生后7天内无持续性动脉导管未闭的正常新生儿，采用泰希霍尔兹法（T）、速度时间积分法（VTI）、庞博法（P）、改良辛普森法（MS）和3D法进行SV比较。采用海科克体表面积公式计算，平均SV分别为33.7 mL/m²（T法）、30.6 mL/m²（VTI法）、22.0 mL/m²（P法）、17.5 mL/m²（3D法）和14.9 mL/m²（MS法）。不同方法测得的每搏输出量差异显著。MS法和3D法之间的相关系数最高。T法和VTI法测得的SV显著高于先前报道的值，似乎不宜用于评估新生儿的容积。3D法和MS法适用于测量新生儿早期的SV。
