Silva Cristina Da, Pedro Fátima, Deister Lizandra, Sahlén Anders, Manouras Aristomenis, Shahgaldi Kambiz
Department of Clinical Physiology Department of Cardiology and Clinical Physiology Department of Cardiology, Karolinska University Hospital, Huddinge, Stockholm, Sweden.
Echocardiography. 2012 Aug;29(7):766-72. doi: 10.1111/j.1540-8175.2012.01695.x. Epub 2012 Apr 11.
Whether measurement of left ventricular outflow tract diameter (LVOTd) using color Doppler (CD) in order to more accurately define LVOTd is more accurate for determination of stroke volume (SV) than gray scale and compare it with direct measurement of LVOT area (a) using three-dimensional echocardiography (3DE) for SV determination.
Twenty-one volunteers were examined. LVOTa was calculated by two-dimensional echocardiography (2DE) using the following formula: π× (d/2)(2) , d = LVOT diameter by gray scale and CD, respectively. Planimetry of LVOTa was performed in parasternal long axis using 3DE. Eccentricity Index was calculated using the lateral and anterior-posterior LVOTd. SV was obtained by four different methods: (1) 2D gray scale, (2) 2D color, (3) LVOTa × LVOT velocity time integral, and (4) SV by Simpson's biplane method. Gray scale LVOTd was significantly smaller compared to LVOTd obtained with CD (P < 0.05). Significant differences occurred between LVOTa gray scale and CD (3.29 ± 0.74 cm(2) vs 3.67 ± 0.70 cm(2) , P < 0.05) and between LVOTa calculated by gray scale in comparison to 3DE planimetry; (3.29 ± 0.74 cm(2) vs 3.61 ± 0.89 cm(2) , P = 0.011). Half of the subjects had at least 17% difference between the lateral and anterior-posterior LVOTd. There were significant differences between SV by 2D gray scale and 2D CD (82.8 ± 17.1 mL vs 92.4 ± 16.8 mL, P < 0.05) and between 2D gray scale and 3DE planimetry (82.8 ± 17.1 mL vs 90.7 ± 19.8 mL, P = 0.025).
Our study demonstrates LVOT being frequently elliptical. SV and LVOTa were found to be similar when comparing 2DE CD and 3DE planimetry and showed higher values in comparison to 2DE gray scale, which suggests 2DE CD to be an alternative approach for SV assessment.
探讨采用彩色多普勒(CD)测量左心室流出道直径(LVOTd)以更准确地定义LVOTd,在测定每搏输出量(SV)方面是否比灰阶更准确,并将其与使用三维超声心动图(3DE)直接测量LVOT面积(a)以测定SV进行比较。
对21名志愿者进行检查。LVOTa通过二维超声心动图(2DE)使用以下公式计算:π×(d/2)²,d分别为灰阶和CD测量的LVOT直径。使用3DE在胸骨旁长轴进行LVOTa的面积测量。使用LVOTd的横向和前后径计算偏心指数。通过四种不同方法获得SV:(1)二维灰阶,(2)二维彩色,(3)LVOTa×LVOT速度时间积分,以及(4)通过Simpson双平面法获得的SV。与CD测量的LVOTd相比,灰阶LVOTd明显更小(P<0.05)。LVOTa的灰阶测量值与CD测量值之间存在显著差异(3.29±0.74cm²对3.67±0.70cm²,P<0.05),并且灰阶计算的LVOTa与3DE面积测量值之间也存在显著差异(3.29±0.74cm²对3.61±0.89cm²,P=0.011)。一半的受试者LVOTd的横向和前后径之间至少有17%的差异。二维灰阶法与二维CD法测得的SV之间存在显著差异(82.8±17.1mL对92.4±16.8mL,P<0.05),二维灰阶法与3DE面积测量法之间也存在显著差异(82.8±17.1mL对90.7±19.8mL,P=0.025)。
我们的研究表明LVOT常为椭圆形。比较2DE CD和3DE面积测量法时,发现SV和LVOTa相似,且与2DE灰阶法相比数值更高,这表明2DE CD是评估SV的一种替代方法。