在健康志愿者中，血浆和血清中的脑源性神经营养因子（BDNF）水平密切相关。
A close correlation between plasma and serum levels of brain-derived neurotrophic factor (BDNF) in healthy volunteers.
机构信息
Department of Psychiatry, University of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, Japan.
出版信息
Int J Psychiatry Clin Pract. 2010 Sep;14(3):220-2. doi: 10.3109/13651501003748560. Epub 2010 Jul 21.
Abstract Objective. Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophic family found in both the central and the peripheral nervous system. Blood BDNF levels are considered as a state marker for depression. Methods. We investigated serum and plasma levels of BDNF levels in 103 healthy volunteers (M/F: 39/64, age: 37±12 years) using ELISA methods. Results and Conclusions. Serum BDNF levels were 14-fold higher than plasma BDNF levels, and a close relationship was found between serum and plasma BDNF levels.
摘要 目的：脑源性神经营养因子（BDNF）是神经营养因子家族的一员，存在于中枢和外周神经系统中。血液 BDNF 水平被认为是抑郁症的状态标志物。方法：我们使用 ELISA 方法检测了 103 名健康志愿者（男/女：39/64，年龄：37±12 岁）的血清和血浆 BDNF 水平。结果与结论：血清 BDNF 水平比血浆 BDNF 水平高 14 倍，并且血清和血浆 BDNF 水平之间存在密切关系。
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