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HIV阳性患者的股骨手术:2005年至2011年的回顾性研究

Surgery of the femur in HIV positive patients: a retrospective review from 2005 to 2011.

作者信息

Cummins F, Ramasubbu B, McCarthy T, Bergin C, Grieve P P

机构信息

Departments of Trauma and Orthopaedics, St James's Hospital, Dublin, Ireland,

出版信息

Ir J Med Sci. 2015 Jun;184(2):505-10. doi: 10.1007/s11845-014-1156-6. Epub 2014 Jun 11.

Abstract

BACKGROUND

There are an estimated 6,900 people with HIV living in Ireland. There is a significant prevalence of femoral osteonecrosis and risk factors for osteoporotic fractures. With this potential, increasing surgical workload, it is important to assess surgical demand and audit outcomes.

METHODS

The hospital's electronic records were examined. Between January 2005 and August 2011, 17 femoral surgeries were identified in seven patients. Patient records were retrospectively reviewed.

RESULTS

Elective operations undertaken were eight hip replacements and one nail dynamisation. Eight emergency operations were undertaken: two DHS, one plating, one nailing, one revision nailing, two incision and drainages and one biopsy. All procedures were carried out using appropriate safety guidelines. Indications for surgery included femoral head osteonecrosis (n = 7), osteomyelitis (n = 3), proximal femoral fracture (n = 2), femoral shaft non-union (n = 1), dynamisation of a nail (n = 1), osteoarthritis (n = 1), fractured femur (n = 1), and revision nailing (n = 1). For two procedures the patient was not on highly active anti-retroviral treatment. All elective patients had CD4 counts greater than 200 pre-operatively. Six patients had undetectable viral loads. Of the eight emergency procedures, four procedures had no preoperative immune status recorded. Complications recorded were three non-unions, one nail fracture, one lesser trochanter fracture and recurrence of osteomyelitis. No surgical site infections were recorded.

CONCLUSIONS

Complications were not related to immune status. The rate of surgical site infection in both elective and emergency procedures was low. The elective surgery patients can safely receive orthopaedic treatment in their regional orthopaedic unit. Due to the high non-infectious complication rates recorded in the emergency group, transfer to a tertiary facility with infectious disease expertise is advised.

摘要

背景

据估计,爱尔兰有6900名艾滋病毒感染者。股骨坏死和骨质疏松性骨折的危险因素普遍存在。鉴于这种可能性以及手术工作量的增加,评估手术需求并审核结果很重要。

方法

检查了医院的电子记录。2005年1月至2011年8月期间,在7名患者中确定了17例股骨手术。对患者记录进行了回顾性审查。

结果

进行的择期手术有8例髋关节置换术和1例髓内钉动力化。进行了8例急诊手术:2例动力髋螺钉固定术、1例钢板固定术、1例髓内钉固定术、1例翻修髓内钉固定术、2例切开引流术和1例活检。所有手术均按照适当的安全指南进行。手术指征包括股骨头坏死(n = 7)、骨髓炎(n = 3)、股骨近端骨折(n = 2)、股骨干不愈合(n = 1)、髓内钉动力化(n = 1)、骨关节炎(n = 1)、股骨骨折(n = 1)和翻修髓内钉固定术(n = 1)。有2例手术患者未接受高效抗逆转录病毒治疗。所有择期手术患者术前CD4细胞计数均大于200。6例患者病毒载量检测不到。在8例急诊手术中,有4例术前未记录免疫状态。记录的并发症有3例不愈合、1例髓内钉骨折、1例小转子骨折和骨髓炎复发。未记录手术部位感染。

结论

并发症与免疫状态无关。择期和急诊手术的手术部位感染率均较低。择期手术患者可以在其当地的骨科单位安全地接受骨科治疗。鉴于急诊组记录的非感染性并发症发生率较高,建议转至具有传染病专业知识的三级医疗机构。

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