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通过简便的无过渡金属串联过程一锅合成苯并[4,5]咪唑并[1,2-a]喹唑啉衍生物

One-pot synthesis of benzo[4,5]imidazo[1,2-a]quinazoline derivatives via facile transition-metal-free tandem process.

作者信息

Fang Shuai, Niu Xiaoyi, Yang Bingchuan, Li Yanqiu, Si Xiaomeng, Feng Lei, Ma Chen

机构信息

Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University , Jinan, 250100, P. R. China.

出版信息

ACS Comb Sci. 2014 Jul 14;16(7):328-32. doi: 10.1021/co500001u. Epub 2014 Jun 20.

Abstract

A one-pot transition metal-free method for synthesizing benzo[4,5]imidazo[1,2-a]quinazoline and imidazo[1,2-a]quinazoline derivatives has been developed. The approach is widely applicable to 2-fluoro-, 2-chloro-, 2-bromo- and 2-nitro-substituted aryl aldehyde and ketone substrates. The fluorescence properties of target compounds were studied.

摘要

已开发出一种用于合成苯并[4,5]咪唑并[1,2-a]喹唑啉和咪唑并[1,2-a]喹唑啉衍生物的无过渡金属一锅法。该方法广泛适用于2-氟、2-氯、2-溴和2-硝基取代的芳基醛和酮底物。研究了目标化合物的荧光性质。

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