疫苗接种时代住院儿童急性乳突炎及复杂或难治性急性中耳炎的微生物学研究
Microbiology of acute mastoiditis and complicated or refractory acute otitis media among hospitalized children in the postvaccination era.
作者信息
Giannakopoulos Polyvios, Chrysovergis Aristeidis, Xirogianni Athanasia, Nikolopoulos Thomas P, Radiotis Alexandros, Lebessi Evangelia, Tsakanikos Michail, Tzanakaki Georgina, Tsolia Maria N
机构信息
From the *ENT Department, "P and A Kyriakou" Children's Hospital, Athens, Greece; †First ENT Department, University of Athens School of Medicine, "Hippokrateion" General Hospital, Athens, Greece; ‡National Meningitis Reference Laboratory, National School of Public Health, Athens, Greece; §Second ENT Department, University of Athens School of Medicine, "Attikon" General Hospital, Athens, Greece; ¶Microbiology Department, "P and A Kyriakou" Children's Hospital, Athens, Greece; and ‖Second Department of Pediatrics, University of Athens School of Medicine, "P and A Kyriakou" Children's Hospital, Athens, Greece.
出版信息
Pediatr Infect Dis J. 2014 Jan;33(1):111-3. doi: 10.1097/INF.0b013e3182a6adb7.
In the post-heptavalent pneumococcal conjugate vaccine era, Streptococcus pneumoniae remains the leading cause of acute mastoiditis and other complicated or refractory acute otitis media among hospitalized children in our settings. Serotype 19A is predominant, invasive and multidrug resistant causing more than half of all mastoiditis cases, two-thirds of cases with subperiosteal abscess and all those requiring mastoidectomy. Continuous surveillance is required.
在七价肺炎球菌结合疫苗时代之后，肺炎链球菌仍是我们所在地区住院儿童急性乳突炎以及其他复杂或难治性急性中耳炎的主要病因。19A 血清型占主导地位，具有侵袭性且对多种药物耐药，导致超过一半的乳突炎病例、三分之二的骨膜下脓肿病例以及所有需要进行乳突切除术的病例。需要持续监测。
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