Alurkar Anand, Prasanna Karanam Lakshmi Sudha, Oak Sagar
King Edward Memorial Hospital, Pune, India.
J Vasc Interv Neurol. 2014 May;7(1):5-7.
Cerebrovascular lesions are uncommon in neurofibromatosis type 1 (NF1).
We report a case of 34-year-old man with NF1 who developed posterior circulation stroke. Diffusion-weighted imaging showed acute infarcts in the right vertebra basilar artery territory. Digital subtraction angiography demonstrated significant stenosis of the basilar artery in the mid segment that was identified as the etiology of the symptoms. The vertebral arteries were tortuous and the basilar artery was ectatic. Subsequently endeavour resolute stent was placed across the lesion and post-procedure angiogram showed resolution of stenosis.
Selective stenotic involvement of the basilar artery with ectatic vertebrobasilar circulation associated with NF1, which was successfully treated with endovascular method, was not been reported previously to our knowledge.
脑血管病变在1型神经纤维瘤病（NF1）中并不常见。
我们报告一例34岁患有NF1的男性发生后循环卒中。弥散加权成像显示右侧椎基底动脉区域急性梗死。数字减影血管造影显示基底动脉中段明显狭窄，确定为症状的病因。椎动脉迂曲，基底动脉扩张。随后成功地在病变处放置了支架，术后血管造影显示狭窄消失。
据我们所知，NF1相关的椎基底动脉循环扩张伴基底动脉选择性狭窄累及此前尚未见报道，而该病例通过血管内方法成功治疗。
