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Hypokalaemia-induced rhabdomyolysis after treatment of post-Kala-azar dermal Leishmaniasis (PKDL) with high-dose AmBisome in Bangladesh-a case report.孟加拉国用高剂量两性霉素B脂质体治疗黑热病后皮肤利什曼病（PKDL）后低钾血症诱发横纹肌溶解——病例报告
PLoS Negl Trop Dis. 2014 Jun 12;8(6):e2864. doi: 10.1371/journal.pntd.0002864. eCollection 2014 Jun.
2
Development of post-kala-azar dermal leishmaniasis in AmBisome treated visceral leishmaniasis: a possible challenge to elimination program in India.两性霉素B脂质体治疗内脏利什曼病后发生的黑热病后皮肤利什曼病：对印度消除计划的一个潜在挑战
J Postgrad Med. 2013 Jul-Sep;59(3):226-8. doi: 10.4103/0022-3859.118046.
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Efficacy of liposomal amphotericin B (AmBisome) in the treatment of persistent post-kala-azar dermal leishmaniasis (PKDL).脂质体两性霉素B（安必素）治疗黑热病后皮肤利什曼病（PKDL）的疗效。
Ann Trop Med Parasitol. 2005 Sep;99(6):563-9. doi: 10.1179/136485905X514127.
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Using focused pharmacovigilance for ensuring patient safety against antileishmanial drugs in Bangladesh's National Kala-azar Elimination Programme.利用重点药物警戒确保孟加拉国国家黑热病消除规划中抗利什曼原虫药物的患者安全。
Infect Dis Poverty. 2018 Aug 13;7(1):80. doi: 10.1186/s40249-018-0461-0.
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Assessing the Efficacy and Safety of Liposomal Amphotericin B and Miltefosine in Combination for Treatment of Post Kala-Azar Dermal Leishmaniasis.评估脂质体两性霉素 B 和米替福新联合治疗内脏利什曼病后皮肤利什曼病的疗效和安全性。
J Infect Dis. 2020 Feb 3;221(4):608-617. doi: 10.1093/infdis/jiz486.
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Case Report: Treatment of Widespread Nodular Post kala-Azar Dermal Leishmaniasis with Extended-Dose Liposomal Amphotericin B in Bangladesh: A Series of Four Cases.病例报告：孟加拉国使用大剂量脂质体两性霉素B治疗广泛结节型黑热病后皮肤利什曼病：四例系列报道
Am J Trop Med Hyg. 2017 Oct;97(4):1111-1115. doi: 10.4269/ajtmh.16-0631. Epub 2017 Aug 18.
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A phase II, non-comparative randomised trial of two treatments involving liposomal amphotericin B and miltefosine for post-kala-azar dermal leishmaniasis in India and Bangladesh.一项在印度和孟加拉国开展的针对晚期内脏利什曼病皮肤利什曼病的两种治疗方法（脂质体两性霉素 B 和米替福新）的 II 期、非对照随机试验。
PLoS Negl Trop Dis. 2024 Jun 20;18(6):e0012242. doi: 10.1371/journal.pntd.0012242. eCollection 2024 Jun.
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Short report: Development of post-kala-azar dermal leishmaniasis (PKDL) in miltefosine-treated visceral leishmaniasis.简短报告：米替福新治疗内脏利什曼病后出现的黑热病后皮肤利什曼病（PKDL）
Am J Trop Med Hyg. 2009 Mar;80(3):336-8.
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Clinical and immunological aspects of post-kala-azar dermal leishmaniasis in Bangladesh.孟加拉国卡拉-azar 后皮肤利什曼病的临床和免疫学方面。
Am J Trop Med Hyg. 2013 Aug;89(2):345-53. doi: 10.4269/ajtmh.12-0711. Epub 2013 Jul 1.
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Post-kala-azar dermal leishmaniasis (PKDL) developing after treatment of visceral leishmaniasis with amphotericin B and miltefosine.在用两性霉素B和米替福新治疗内脏利什曼病后出现的黑热病后皮肤利什曼病（PKDL）。
Ann Trop Med Parasitol. 2009 Dec;103(8):727-30. doi: 10.1179/000349809X12554106963438.

引用本文的文献

1
A phase II, non-comparative randomised trial of two treatments involving liposomal amphotericin B and miltefosine for post-kala-azar dermal leishmaniasis in India and Bangladesh.一项在印度和孟加拉国开展的针对晚期内脏利什曼病皮肤利什曼病的两种治疗方法（脂质体两性霉素 B 和米替福新）的 II 期、非对照随机试验。
PLoS Negl Trop Dis. 2024 Jun 20;18(6):e0012242. doi: 10.1371/journal.pntd.0012242. eCollection 2024 Jun.
2
Case Report: An Atypical Case of Post-Kala-Azar Dermal Leishmaniasis with Ulcers and Verrucous Lesions: Clinical and Therapeutic Implications.病例报告：伴有溃疡和疣状损害的黑热病后皮肤利什曼病的非典型病例：临床和治疗意义。
Am J Trop Med Hyg. 2023 Nov 27;110(1):40-43. doi: 10.4269/ajtmh.23-0448. Print 2024 Jan 3.
3
Safety and efficacy of paromomycin/miltefosine/liposomal amphotericin B combinations for the treatment of post-kala-azar dermal leishmaniasis in Sudan: A phase II, open label, randomized, parallel arm study.标题：巴龙霉素/米替福新/脂质体两性霉素 B 联合治疗苏丹内脏利什曼病后皮肤利什曼病的安全性和有效性：一项 II 期、开放标签、随机、平行臂研究。 **解析**： - 原文：“Safety and efficacy of paromomycin/miltefosine/liposomal amphotericin B combinations for the treatment of post-kala-azar dermal leishmaniasis in Sudan: A phase II, open label, randomized, parallel arm study.” - 译文：“巴龙霉素/米替福新/脂质体两性霉素 B 联合治疗苏丹内脏利什曼病后皮肤利什曼病的安全性和有效性：一项 II 期、开放标签、随机、平行臂研究。”
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Post kala-azar dermal leishmaniasis in the Indian sub-continent: challenges and strategies for elimination.印度次大陆的无黑热病皮肤利什曼病：消除的挑战与策略。
Front Immunol. 2023 Aug 11;14:1236952. doi: 10.3389/fimmu.2023.1236952. eCollection 2023.
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Open Forum Infect Dis. 2023 May 2;10(5):ofad231. doi: 10.1093/ofid/ofad231. eCollection 2023 May.
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Voriconazole- induced severe hypokalemic rhabdomyolysis: A case report.伏立康唑诱发的严重低钾性横纹肌溶解症：一例报告。
Int J Pediatr Adolesc Med. 2022 Mar;9(1):66-68. doi: 10.1016/j.ijpam.2021.03.007. Epub 2021 Mar 21.
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Therapeutic Modalities in Post Kala-azar Dermal Leishmaniasis: A Systematic Review of the Effectiveness and Safety of the Treatment Options.黑热病后皮肤利什曼病的治疗方式：治疗选择的有效性和安全性的系统评价
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Post kala-azar dermal leishmaniasis: A threat to elimination program.无鞭毛体利什曼原虫病皮肤后：消除规划的威胁。
PLoS Negl Trop Dis. 2020 Jul 2;14(7):e0008221. doi: 10.1371/journal.pntd.0008221. eCollection 2020 Jul.
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Report of the Fifth Post-Kala-Azar Dermal Leishmaniasis Consortium Meeting, Colombo, Sri Lanka, 14-16 May 2018.2018 年 5 月 14 日至 16 日，第五届卡拉胶后皮肤利什曼病联合会议在斯里兰卡科伦坡举行。
Parasit Vectors. 2020 Mar 30;13(1):159. doi: 10.1186/s13071-020-04011-7.
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A Novel Compound Heterozygous Variant Causes 17α-Hydroxylase/17, 20-Lyase Deficiency.一种新型复合杂合变异导致17α-羟化酶/17,20-裂解酶缺乏症。
Front Genet. 2019 Oct 22;10:996. doi: 10.3389/fgene.2019.00996. eCollection 2019.

本文引用的文献

1
Does lipid emulsion reduce amphotericin B nephrotoxicity? A systematic review and meta-analysis.脂质体能否降低两性霉素 B 的肾毒性？系统评价和荟萃分析。
Clin Infect Dis. 2012 Jun;54(12):1774-7. doi: 10.1093/cid/cis290. Epub 2012 Apr 5.
2
Liposomal amphotericin B for visceral leishmaniasis in human immunodeficiency virus-coinfected patients: 2-year treatment outcomes in Bihar, India.脂质体两性霉素 B 治疗人免疫缺陷病毒合并内脏利什曼病患者：印度比哈尔邦的 2 年治疗结局。
Clin Infect Dis. 2011 Oct;53(7):e91-8. doi: 10.1093/cid/cir521.
3
Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial.印度内脏利什曼病短程多药治疗与标准治疗的比较：一项开放标签、非劣效性、随机对照试验。
Lancet. 2011 Feb 5;377(9764):477-86. doi: 10.1016/S0140-6736(10)62050-8. Epub 2011 Jan 20.
4
Ambisome plus miltefosine for Indian patients with kala-azar.两性霉素 B 脂质体加米替福新治疗印度黑热病患者。
Trans R Soc Trop Med Hyg. 2011 Feb;105(2):115-7. doi: 10.1016/j.trstmh.2010.10.008. Epub 2010 Dec 3.
5
Enhanced case detection and improved diagnosis of PKDL in a Kala-azar-endemic area of Bangladesh.提高孟加拉国黑热病流行地区内脏利什曼病的病例检出率和诊断率。
PLoS Negl Trop Dis. 2010 Oct 5;4(10):e832. doi: 10.1371/journal.pntd.0000832.
6
Dietary pattern, nutritional status, anaemia and anaemia-related knowledge in urban adolescent college girls of Bangladesh.孟加拉国城市青春期女大学生的饮食模式、营养状况、贫血及贫血相关知识
J Pak Med Assoc. 2010 Aug;60(8):633-8.
7
Long-term intermittent multiple micronutrient supplementation enhances hemoglobin and micronutrient status more than iron + folic acid supplementation in Bangladeshi rural adolescent girls with nutritional anemia.在患有营养性贫血的孟加拉农村少女中，长期间歇性补充多种微量营养素比补充铁 + 叶酸更能提高血红蛋白和微量营养素水平。
J Nutr. 2010 Oct;140(10):1879-86. doi: 10.3945/jn.109.119123. Epub 2010 Aug 11.
8
Effectiveness and safety of liposomal amphotericin B for visceral leishmaniasis under routine program conditions in Bihar, India.印度比哈尔邦常规规划条件下脂质体两性霉素 B 治疗内脏利什曼病的疗效和安全性。
Am J Trop Med Hyg. 2010 Aug;83(2):357-64. doi: 10.4269/ajtmh.2010.10-0156.
9
A curative immune profile one week after treatment of Indian kala-azar patients predicts success with a short-course liposomal amphotericin B therapy.印度黑热病患者治疗一周后具有治愈性免疫特征，预示着采用短程脂质体两性霉素 B 治疗可取得成功。
PLoS Negl Trop Dis. 2010 Jul 27;4(7):e764. doi: 10.1371/journal.pntd.0000764.
10
Drug-induced nephrotoxicity caused by amphotericin B lipid complex and liposomal amphotericin B: a review and meta-analysis.两性霉素B脂质复合物和两性霉素B脂质体引起的药物性肾毒性：综述与荟萃分析
Medicine (Baltimore). 2010 Jul;89(4):236-244. doi: 10.1097/MD.0b013e3181e9441b.

Hypokalaemia-induced rhabdomyolysis after treatment of post-Kala-azar dermal Leishmaniasis (PKDL) with high-dose AmBisome in Bangladesh-a case report.

作者信息

Marking Ulrika, den Boer Margriet, Das Asish Kumar, Ahmed Elshafie Mohamed, Rollason Victoria, Ahmed Be-Nazir, Davidson Robert N, Ritmeijer Koert

机构信息

Médecins Sans Frontières, Amsterdam, The Netherlands.

Division of Clinical Pharmacology and Toxicology, University Hospitals of Geneva, Geneva, Switzerland.

出版信息

PLoS Negl Trop Dis. 2014 Jun 12;8(6):e2864. doi: 10.1371/journal.pntd.0002864. eCollection 2014 Jun.

DOI:10.1371/journal.pntd.0002864
PMID:24922279
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4055542/
Abstract
摘要