克隆的曼氏血吸虫蛋白酶（血红蛋白酶）作为一种潜在的血清学诊断试剂。
Cloned Schistosoma mansoni proteinase (hemoglobinase) as a putative serodiagnostic reagent.
作者信息
Chappell C L, Hackel J, Davis A H
机构信息
Verna and Marrs McLean Department of Biochemistry, Baylor College of Medicine, Houston, Texas 77030.
出版信息
J Clin Microbiol. 1989 Jan;27(1):196-8. doi: 10.1128/jcm.27.1.196-198.1989.
Abstract
Expressed cDNA encoding a proteolytic enzyme from Schistosoma mansoni has been cloned recently. Circulating antibodies reacting with the recombinant protein have been detected in the blood of mice and humans infected with S. mansoni, S. japonicum, or S. haematobium. S. mansoni and S. haematobium infection can be distinguished by antibody titer.
摘要
最近克隆出了编码曼氏血吸虫一种蛋白水解酶的cDNA。在感染曼氏血吸虫、日本血吸虫或埃及血吸虫的小鼠和人类血液中检测到了与重组蛋白发生反应的循环抗体。曼氏血吸虫感染和埃及血吸虫感染可通过抗体滴度加以区分。
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