Heller K E
Institute of Population Biology, Universitetsparken 15, 21oo Copenhagen Denmark.
Behav Processes. 1984 Jan;9(1):61-72. doi: 10.1016/0376-6357(84)90008-1.
Two experiments were conducted to examine effects of repeated exposure to electric footshock on subsequent agonistic behaviour and adrenocortical secretion in male mice of different androgen status. Aggressive and submissive behavioural components were independently studied in the two experiments. It was found that repetition reduced aggressive, and stimulated submissive and adrenocortical responses to shock, particularly in castrates. The direction of the shock effects on aggressive behaviour was reversed by repetition in castrates, whereas only the magnitude of the behavioural responses was changed at normal androgen levels. It is suggested that the changes in agonistic responses to shock induced by repetition are mediated by changes in pituitary-adrenocortical secretion, and that androgen inhibits the shock effects on agonistic behaviour through inhibition of the pituitary-adrenocortical responses to shock.
进行了两项实验，以检验反复暴露于足部电击对不同雄激素状态的雄性小鼠随后的攻击行为和肾上腺皮质分泌的影响。在这两项实验中分别独立研究了攻击性行为和顺从性行为成分。结果发现，反复暴露会降低攻击性，并刺激对电击的顺从性和肾上腺皮质反应，尤其是在去势小鼠中。在去势小鼠中，反复暴露会使电击对攻击行为的影响方向发生逆转，而在正常雄激素水平下，仅行为反应的幅度发生了变化。研究表明，反复暴露引起的对电击的攻击反应变化是由垂体 - 肾上腺皮质分泌的变化介导的，并且雄激素通过抑制垂体 - 肾上腺皮质对电击的反应来抑制电击对攻击行为的影响。
