通过多功能金-氧化锌杂化纳米颗粒靶向溶酶体膜通透化以诱导癌细胞凋亡并进行成像。
Targeting lysosomal membrane permeabilization to induce and image apoptosis in cancer cells by multifunctional Au-ZnO hybrid nanoparticles.
作者信息
Gao Wen, Cao Wenhua, Zhang Huaibin, Li Ping, Xu Kehua, Tang Bo
机构信息
College of Chemistry, Chemical Engineering and Materials Science, Synergetic Innovation Center of Chemical Imaging Functionalized Probes, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P.R. China.
出版信息
Chem Commun (Camb). 2014 Aug 4;50(60):8117-20. doi: 10.1039/c4cc03793f.
PMID:24924212
Abstract
We have developed multifunctional Au-ZnO hybrid nanoparticles (NPs) for targeted induction lysosomal membrane permeabilization (LMP)-dependent apoptosis in cancer cells and real-time imaging.
摘要
我们已经开发出多功能金-氧化锌混合纳米颗粒（NPs），用于靶向诱导癌细胞中依赖溶酶体膜通透性（LMP）的凋亡以及实时成像。
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