Cooper James K
Department of Medicine/Geriatrics and Palliative Care, George Washington University Medical Center, Washington, DC, USA.
Neurobiol Aging. 2014 Sep;35 Suppl 2:S79-83. doi: 10.1016/j.neurobiolaging.2014.02.029. Epub 2014 May 15.
The knowledge base of nutrition and the brain is steadily expanding. Much of the research is aimed at ways to protect the brain from damage. In adults, the major causes of brain damage are aging and dementia. The most prominent dementia, and the condition that grabs the most public attention, is Alzheimer's disease. The assumption in the field is that possibly some change in nutrition could protect the brain and prevent, delay, or minimize Alzheimer's disease damage. Presented here is a framework for understanding the implications of this research. There is a gap between publishing research results and change in public nutrition behavior. Several influencing elements intervene. These include regulatory agencies and all the organizations and people who advise the public, all with their own perspectives. In considering what advice to give, advisors may consider effectiveness, research model, persuasiveness, and risks, among other factors. Advice about nutrition and Alzheimer's disease today requires several caveats.
营养与大脑的知识库正在稳步扩展。许多研究旨在探寻保护大脑免受损伤的方法。在成年人中,脑损伤的主要原因是衰老和痴呆。最突出的痴呆症,也是最受公众关注的病症,是阿尔茨海默病。该领域的假设是,营养方面的某些变化可能保护大脑,并预防、延缓或最小化阿尔茨海默病造成的损害。本文提出了一个理解这项研究意义的框架。在发表研究结果与公众营养行为改变之间存在差距。有几个影响因素介入其中。这些因素包括监管机构以及所有向公众提供建议的组织和人员,他们都有自己的观点。在考虑给出何种建议时,顾问们可能会考虑有效性、研究模式、说服力和风险等因素。如今,关于营养与阿尔茨海默病的建议需要一些注意事项。