Barnard Neal D, Bush Ashley I, Ceccarelli Antonia, Cooper James, de Jager Celeste A, Erickson Kirk I, Fraser Gary, Kesler Shelli, Levin Susan M, Lucey Brendan, Morris Martha Clare, Squitti Rosanna
Department of Medicine, George Washington University School of Medicine, Washington, DC, USA; Physicians Committee for Responsible Medicine, Washington, DC, USA.
Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.
Neurobiol Aging. 2014 Sep;35 Suppl 2:S74-8. doi: 10.1016/j.neurobiolaging.2014.03.033. Epub 2014 May 14.
Risk of developing Alzheimer's disease is increased by older age, genetic factors, and several medical risk factors. Studies have also suggested that dietary and lifestyle factors may influence risk, raising the possibility that preventive strategies may be effective. This body of research is incomplete. However, because the most scientifically supported lifestyle factors for Alzheimer's disease are known factors for cardiovascular diseases and diabetes, it is reasonable to provide preliminary guidance to help individuals who wish to reduce their risk. At the International Conference on Nutrition and the Brain, Washington, DC, July 19-20, 2013, speakers were asked to comment on possible guidelines for Alzheimer's disease prevention, with an aim of developing a set of practical, albeit preliminary, steps to be recommended to members of the public. From this discussion, 7 guidelines emerged related to healthful diet and exercise habits.
年龄增长、遗传因素以及多种医学风险因素会增加患阿尔茨海默病的风险。研究还表明，饮食和生活方式因素可能会影响患病风险，这增加了预防策略可能有效的可能性。这一系列研究并不完整。然而，由于对阿尔茨海默病而言，最具科学依据的生活方式因素也是心血管疾病和糖尿病的已知因素，因此为希望降低风险的个人提供初步指导是合理的。在2013年7月19日至20日于华盛顿特区举行的营养与大脑国际会议上，要求发言者对阿尔茨海默病预防的可能指导方针发表评论，目的是制定一套切实可行的（尽管是初步的）步骤，推荐给公众。从这次讨论中，得出了7条与健康饮食和运动习惯相关的指导方针。
