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巴泽克斯综合征揭示了一例胃癌。

Bazex syndrome revealing a gastric cancer.

作者信息

Robert Maxime, Gilabert Marine, Rahal Soraya, Ries Pauline, Raoul Jean-Luc

机构信息

Department of Medical Oncology, Paoli-Calmettes Institute, Marseille, France.

出版信息

Case Rep Oncol. 2014 Apr 30;7(1):285-7. doi: 10.1159/000362787. eCollection 2014 Jan.

DOI:10.1159/000362787
PMID:24926258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4036134/
Abstract

We herein report the case of a 73-year-old woman who developed skin and nail disorders 2 months before her digestive symptoms started, which lead to the diagnosis of gastric adenocarcinoma. The lesions were diagnosed as Bazex syndrome, usually seen in squamous cell carcinoma. Under systemic chemotherapy, the cutaneous signs improved for some months before worsening when the disease progressed.

摘要

我们在此报告一例73岁女性病例,该患者在出现消化系统症状前2个月出现皮肤和指甲病变,最终诊断为胃腺癌。这些病变被诊断为Bazex综合征,通常见于鳞状细胞癌。在全身化疗期间,皮肤症状在疾病进展恶化前数月有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/176c/4036134/050cc691454c/cro-0007-0285-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/176c/4036134/050cc691454c/cro-0007-0285-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/176c/4036134/050cc691454c/cro-0007-0285-g01.jpg

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Skin Appendage Disord. 2021 Apr;7(3):163-172. doi: 10.1159/000513828. Epub 2021 Mar 2.
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本文引用的文献

1
Diagnosis and treatment of cutaneous paraneoplastic disorders.皮肤副肿瘤性疾病的诊断与治疗。
Dermatol Ther. 2010 Nov-Dec;23(6):662-75. doi: 10.1111/j.1529-8019.2010.01371.x.
2
Paraneoplastic acrokeratosis (bazex syndrome) in lung cancer.肺癌中的副肿瘤性肢端角化症(巴泽克斯综合征)
J Clin Oncol. 2009 Dec 20;27(36):e266-8. doi: 10.1200/JCO.2009.22.6852. Epub 2009 Oct 13.
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Acrokeratosis paraneoplastica (Bazex' syndrome) associated with metastatic squamous cell esophageal carcinoma.
伴有低白蛋白血症和严重腹水的巴泽克斯综合征
Case Rep Oncol. 2016 Jul 29;9(2):405-408. doi: 10.1159/000448168. eCollection 2016 May-Aug.
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Cutaneous manifestations of internal malignancies: an overview.内部恶性肿瘤的皮肤表现:综述
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Bazex syndrome: acrokeratosis paraneoplastica.巴泽克斯综合征:副肿瘤性肢端角化病。
Semin Dermatol. 1995 Jun;14(2):84-9. doi: 10.1016/s1085-5629(05)80002-1.
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Acrokeratosis paraneoplastica (Bazex' syndrome).副肿瘤性肢端角化病(巴泽克斯综合征)。
J Am Acad Dermatol. 1987 Jan;16(1 Pt 2):178-83. doi: 10.1016/s0190-9622(87)80057-9.